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Table 4 Univariate and multivariate analyses for all patients who underwent surgery

From: Efficacy of interleukin-6 in combination with D-dimer in predicting early poor postoperative prognosis after acute stanford type a aortic dissection

Variable Univariate Model Multivariate Model
OR 95% CI p-value OR 95% CI p-value
Age, years
  < 60 REF      
  ≥ 60 1.016 0.423–2.438 0.885    
BMI, kg/m
 <25 REF      
  ≥ 25 0.621 0.286–1.349 0.228    
Sex
 Female REF      
 Male 1.067 0.443–2.566 0.885    
IL-6(pg/mL)
  ≤ 108 REF    REF   
 >108 33.662 11.906–95.178 <0.001 24.937 6.837–90.931 <0.001
D-dimer (ug/mL)
  ≤ 14.0 REF    REF   
 >14.0 24.706 8.884–68.705 <0.001 18.757 5.094–69.075 <0.001
PT (sec)
  ≤ 15.0 REF    REF   
  > 15.0 2.667 1.12–6.346 0.027 1.198 0.268–5.350 0.813
Heamoglobin (10ˆ9/L)
  ≤ 10 REF      
 >10 0.979 0.419–2.285 0.961    
Neutrophile granulocyte (10ˆ9/L)
  ≤ 7.0 REF      
 >7.0 0.942 0.361–2.456 0.942    
Leukomonocyte (10ˆ9/L)
  ≤ 0.8 REF      
 >0.8 0.545 0.241–1.235 0.146    
Hemoglobin (g/L)
  ≥ 120 REF      
 <120 0.77 0.326–1.820 0.552    
Albumin (g/L)
  ≥ 35.0 REF      
 <35.0 0.565 0.256–1.427 0.157    
Troponin-I (ug/L)
  ≤ 0.02 REF      
 >0.02 1.229 0.568–2.662 0.601    
NT-ProBNP (pg/mL)
  ≤ 349 REF      
 >349 1.442 0.663–3.135 0.356    
Serum creatinine (umol/L)
  ≤ 135 REF    REF   
 >135 2.365 0.982–5.696 0.055 1.965 0.493–7.829 0.338
Lactic acid (mmol/L)
  ≤ 2.5 REF      
 >2.5 2.287 0.735–7.116 0.153    
Alanine aminotransferase (IU/L)
  ≤ 40 REF      
 >40 0.650 0.285–1.483 0.306    
Aspartate aminotransferase (IU/L)
  ≤ 46 REF      
 >46 0.605 0.258–1.415 0.246    
EF (%)
  ≥ 60.0 REF      
 <60.0 1.128 0.431–2.954 0.807    
Marfan Syndrome
 no REF      
 yes 1.275 0.236–6.891 0.778    
Hypertension
 no REF      
 yes 2.469 0.505–12.080 0.265    
Diabetes
 no REF      
 yes 0.33 0.040–2.703 0.302    
Pericardial effusion (Medium or above)
 no REF      
 yes 3.281 0.444–24.234 0.244    
MPS
 no REF      
 yes 1.877 0.583–6.043 0.291    
AR (Medium or above)
 no REF      
 yes 0.731 0.287–1.866     
History of cardiac surgery
 no REF      
 yes 1.65 0.464–5.863 0.439    
Operative time (min)
  ≤ 306 REF    REF   
 >306 1.962 0.899–4.279 0.09 3.635 0.977–13.521 0.054
CPB time (min)
  ≤ 149 REF      
 >149 0.894 0.409–1.952 0.779    
Aortic Clamp time (min)
  ≤ 51 REF      
 >51 1.324 0.601–2.920 0.486    
SBP time (min)
  ≤ 9.7 REF      
 >9.7 1.037 0.468–2.296 0.929    
CA time (min)
  ≤ 3.1 REF      
 >3.1 1.121 0.489–2.568 0.787    
Aortic Root Concomitant procedure
 no REF      
 yes 0.659 0.294–1.478 0.312