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Table 4 Univariate and multivariate analyses for all patients who underwent surgery

From: Efficacy of interleukin-6 in combination with D-dimer in predicting early poor postoperative prognosis after acute stanford type a aortic dissection

Variable

Univariate Model

Multivariate Model

OR

95% CI

p-value

OR

95% CI

p-value

Age, years

  < 60

REF

     

  ≥ 60

1.016

0.423–2.438

0.885

   

BMI, kg/m

 <25

REF

     

  ≥ 25

0.621

0.286–1.349

0.228

   

Sex

 Female

REF

     

 Male

1.067

0.443–2.566

0.885

   

IL-6(pg/mL)

  ≤ 108

REF

  

REF

  

 >108

33.662

11.906–95.178

<0.001

24.937

6.837–90.931

<0.001

D-dimer (ug/mL)

  ≤ 14.0

REF

  

REF

  

 >14.0

24.706

8.884–68.705

<0.001

18.757

5.094–69.075

<0.001

PT (sec)

  ≤ 15.0

REF

  

REF

  

  > 15.0

2.667

1.12–6.346

0.027

1.198

0.268–5.350

0.813

Heamoglobin (10ˆ9/L)

  ≤ 10

REF

     

 >10

0.979

0.419–2.285

0.961

   

Neutrophile granulocyte (10ˆ9/L)

  ≤ 7.0

REF

     

 >7.0

0.942

0.361–2.456

0.942

   

Leukomonocyte (10ˆ9/L)

  ≤ 0.8

REF

     

 >0.8

0.545

0.241–1.235

0.146

   

Hemoglobin (g/L)

  ≥ 120

REF

     

 <120

0.77

0.326–1.820

0.552

   

Albumin (g/L)

  ≥ 35.0

REF

     

 <35.0

0.565

0.256–1.427

0.157

   

Troponin-I (ug/L)

  ≤ 0.02

REF

     

 >0.02

1.229

0.568–2.662

0.601

   

NT-ProBNP (pg/mL)

  ≤ 349

REF

     

 >349

1.442

0.663–3.135

0.356

   

Serum creatinine (umol/L)

  ≤ 135

REF

  

REF

  

 >135

2.365

0.982–5.696

0.055

1.965

0.493–7.829

0.338

Lactic acid (mmol/L)

  ≤ 2.5

REF

     

 >2.5

2.287

0.735–7.116

0.153

   

Alanine aminotransferase (IU/L)

  ≤ 40

REF

     

 >40

0.650

0.285–1.483

0.306

   

Aspartate aminotransferase (IU/L)

  ≤ 46

REF

     

 >46

0.605

0.258–1.415

0.246

   

EF (%)

  ≥ 60.0

REF

     

 <60.0

1.128

0.431–2.954

0.807

   

Marfan Syndrome

 no

REF

     

 yes

1.275

0.236–6.891

0.778

   

Hypertension

 no

REF

     

 yes

2.469

0.505–12.080

0.265

   

Diabetes

 no

REF

     

 yes

0.33

0.040–2.703

0.302

   

Pericardial effusion (Medium or above)

 no

REF

     

 yes

3.281

0.444–24.234

0.244

   

MPS

 no

REF

     

 yes

1.877

0.583–6.043

0.291

   

AR (Medium or above)

 no

REF

     

 yes

0.731

0.287–1.866

    

History of cardiac surgery

 no

REF

     

 yes

1.65

0.464–5.863

0.439

   

Operative time (min)

  ≤ 306

REF

  

REF

  

 >306

1.962

0.899–4.279

0.09

3.635

0.977–13.521

0.054

CPB time (min)

  ≤ 149

REF

     

 >149

0.894

0.409–1.952

0.779

   

Aortic Clamp time (min)

  ≤ 51

REF

     

 >51

1.324

0.601–2.920

0.486

   

SBP time (min)

  ≤ 9.7

REF

     

 >9.7

1.037

0.468–2.296

0.929

   

CA time (min)

  ≤ 3.1

REF

     

 >3.1

1.121

0.489–2.568

0.787

   

Aortic Root Concomitant procedure

 no

REF

     

 yes

0.659

0.294–1.478

0.312

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