Fig. 1

Mouse mortality and incidence of abdominal aortic aneurysms, and the heart and aorta gross appearance. a: ATRA reduces Ang II-induced AAA incidence and mortality in ApoE^−/− mice. Mortality = Number of deaths/Number of mice in each group. AAA incidence = Number of AAAs/Number of mice in each group. If a mouse died within 28 days, an autopsy was conducted to confirm massive hemorrhage caused by a ruptured abdominal aortic aneurysm. Mice were also diagnosed with AAA. b. Repressentative pictures of suprarenal abdominal aortic morphology identified in different groups. (as indicated by the black arrowheads). Scale bar is 5 mm