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Table 1 Baseline characteristics of the included patients

From: Characteristics and outcomes of Stanford type A aortic dissection patients with severe post-operation hyperbilirubinemia: a retrospective cohort study

Variables Value
Preoperative
 Age, mean ± SD (years) 49.1 ± 11.0
 Male, n (%) 223 (82.3%)
 Co-morbidity
  Hypertension, n (%) 158 (58.3%)
  Diabetes, n (%) 3 (1.1%)
  Cerebrovascular disease, n (%) 16 (5.9%)
  Previous cardiac surgery, n (%) 8 (2.9%)
 APACHEII score, mean ± SD 9.2 ± 3.2
 MELD score, mean ± SD 9.2 ± 4.1
 SOFA score, mean ± SD 2.1 ± 1.5
 MAP, mean ± SD (mm/Hg) 90.5 ± 12.9 (70–105)
 TB, mean ± SD (μmol/l) ↑25.0 ± 15.0 (3.4–20.5)
 CB, mean ± SD (μmol/l) ↑7.8 ± 8.1 (0.0–6.8)
 WBC, mean ± SD (109/l) ↑11.7 ± 5.0 (3.5–9.5)
 Hb, mean ± SD (g/l) 136.1 ± 19.9 (130–175)
 PLT, mean ± SD (109 /l) ↑157.2 ± 68.5 (125–350)
 SCr, mean ± SD (μmol/l) ↑111.1 ± 38.3 (57–111)
 PT, mean ± SD (s) 12.0 ± 2.2 (9.8–12.1)
Intraoperative
 Type of operation
  Ascending aorta, n (%) 227 (83.8%)
  Aortic valve 191 (70.7%)
  Aortic arch, n (%) 233 (86%)
  Coronary artery, n (%) 46 (17%)
 Operation duration, mean ± SD (h) 6.8 ± 1.6
 CPB time, mean ± SD (min) 226.5 ± 60.9
 ACC time, mean ± SD (min) 102.2 ± 28.0
 Arrest time, mean ± SD (min) 25.1 ± 14.4
 The amount of blood transfusion (U) 18.8 ± 10.6
Postoperative
 APACHE II score 16.9 ± 2.5
 SOFA score 12.1 ± 2.6
 Meld score 18.6 ± 4.4
 AST, mean ± SD (U /L) ↑347.6 ± 1387.2 (9–50)
 ALT, mean ± SD (U/L) ↑164.4 ± 526.6 (9–50)
 TB, mean ± SD (μmol /l) ↑189.1 ± 74.6 (3.4–20.5)
 CB, mean ± SD (μmol /l) ↑110.7 ± 37.9 (0.0–6.8)
 WBC, mean ± SD (109/l) ↑12.9 ± 4.8 (3.5–9.5)
 Hb, mean ± SD (g/l) 112.9 ± 16.6 (130–175)
 PLT, mean ± SD (109 /l) ↓99.8 ± 49.5 (125–350)
 SCr, mean ± SD (μmol/l) ↑162.8 ± 71.8 (57–111)
 PT, mean ± SD (s) 13.6 ± 2.9 (9.8–12.1)
 Peak TB level, mean ± SD (μmol/l) 150.9 ± 93.0
 Peak TB level > 171 μmol/l, n (%) 55 (20.4%)
 Peak TB level > 340 μmol/l, n (%) 12 (4.4%)
 Time to peak TB level, mean ± SD (d) 3.8 ± 3.0
 Time to peak TB level > 5 d, n (%) 47 (17.4%)
  1. ACC Aortic cross clamp, APACHEII Acute physiology and chronic health evaluation II, CB Conjugated bilirubin, CPB Cardiopulmonary bypass, Hb Hemoglobin, MAP Mean arterial pressure, MELD Model for end-stage liver disease, min minute, PLT Platelet, PT Prothrombin time, SCr Serum creatinine, SD Standard deviation, SOFA Sequential organ failure assessment, TB Total bilirubin, WBC White blood cell
  2. Parentheses provide normal ranges for the depicted values; ↑ indicate variables greater than normal range and ↓ indicate variables less than normal range