|
Preoperative
|
|
Age, mean ± SD (years)
|
49.1 ± 11.0
|
|
Male, n (%)
|
223 (82.3%)
|
|
Co-morbidity
|
|
Hypertension, n (%)
|
158 (58.3%)
|
|
Diabetes, n (%)
|
3 (1.1%)
|
|
Cerebrovascular disease, n (%)
|
16 (5.9%)
|
|
Previous cardiac surgery, n (%)
|
8 (2.9%)
|
|
APACHEII score, mean ± SD
|
9.2 ± 3.2
|
|
MELD score, mean ± SD
|
9.2 ± 4.1
|
|
SOFA score, mean ± SD
|
2.1 ± 1.5
|
|
MAP, mean ± SD (mm/Hg)
|
90.5 ± 12.9 (70–105)
|
|
TB, mean ± SD (μmol/l)
|
↑25.0 ± 15.0 (3.4–20.5)
|
|
CB, mean ± SD (μmol/l)
|
↑7.8 ± 8.1 (0.0–6.8)
|
|
WBC, mean ± SD (109/l)
|
↑11.7 ± 5.0 (3.5–9.5)
|
|
Hb, mean ± SD (g/l)
|
136.1 ± 19.9 (130–175)
|
|
PLT, mean ± SD (109 /l)
|
↑157.2 ± 68.5 (125–350)
|
|
SCr, mean ± SD (μmol/l)
|
↑111.1 ± 38.3 (57–111)
|
|
PT, mean ± SD (s)
|
12.0 ± 2.2 (9.8–12.1)
|
|
Intraoperative
|
|
Type of operation
|
|
Ascending aorta, n (%)
|
227 (83.8%)
|
|
Aortic valve
|
191 (70.7%)
|
|
Aortic arch, n (%)
|
233 (86%)
|
|
Coronary artery, n (%)
|
46 (17%)
|
|
Operation duration, mean ± SD (h)
|
6.8 ± 1.6
|
|
CPB time, mean ± SD (min)
|
226.5 ± 60.9
|
|
ACC time, mean ± SD (min)
|
102.2 ± 28.0
|
|
Arrest time, mean ± SD (min)
|
25.1 ± 14.4
|
|
The amount of blood transfusion (U)
|
18.8 ± 10.6
|
|
Postoperative
|
|
APACHE II score
|
16.9 ± 2.5
|
|
SOFA score
|
12.1 ± 2.6
|
|
Meld score
|
18.6 ± 4.4
|
|
AST, mean ± SD (U /L)
|
↑347.6 ± 1387.2 (9–50)
|
|
ALT, mean ± SD (U/L)
|
↑164.4 ± 526.6 (9–50)
|
|
TB, mean ± SD (μmol /l)
|
↑189.1 ± 74.6 (3.4–20.5)
|
|
CB, mean ± SD (μmol /l)
|
↑110.7 ± 37.9 (0.0–6.8)
|
|
WBC, mean ± SD (109/l)
|
↑12.9 ± 4.8 (3.5–9.5)
|
|
Hb, mean ± SD (g/l)
|
112.9 ± 16.6 (130–175)
|
|
PLT, mean ± SD (109 /l)
|
↓99.8 ± 49.5 (125–350)
|
|
SCr, mean ± SD (μmol/l)
|
↑162.8 ± 71.8 (57–111)
|
|
PT, mean ± SD (s)
|
13.6 ± 2.9 (9.8–12.1)
|
|
Peak TB level, mean ± SD (μmol/l)
|
150.9 ± 93.0
|
|
Peak TB level > 171 μmol/l, n (%)
|
55 (20.4%)
|
|
Peak TB level > 340 μmol/l, n (%)
|
12 (4.4%)
|
|
Time to peak TB level, mean ± SD (d)
|
3.8 ± 3.0
|
|
Time to peak TB level > 5 d, n (%)
|
47 (17.4%)
|
