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Table 4 Logistic regression analysis for in-hospital mortality

From: Characteristics and outcomes of Stanford type A aortic dissection patients with severe post-operation hyperbilirubinemia: a retrospective cohort study

Characteristic

Univariate logistic regression

Multivariate logistic regression (model 1)

Multivariate logistic regression (model 2)

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

Age (year)

1.035 (1.009–1.062)

0.008

1.005 (1.004–1.099)

0.033

1.046 (1.002–1.093)

0.040

Male (yes/no)

2.483 (1.106–5.575)

0.027

    

Preoperative

 SCr

1.009 (1.002–1.016)

0.008

    

 APACHE II score

1.178 (1.082–1.282)

< 0.001

    

Intraoperative

 CPB time

1.007 (1.003–1.011)

0.002

    

 ACC time

1.012 (1.002–1.021)

0.014

    

 Deep hypothermic circulatory arrest time

0.997 (0.979–1.016)

0.787

    

Postoperative

 MAP

0.948 (0.926–0.971)

< 0.001

0.955 (0.922–0.990)

0.012

0.963 (0.930–0.977)

0.031

 Re-operation (yes/no)

3.611 (1.324–9.852)

0.012

    

 The total amount of blood transfusion

1.046 (1.032–1.060)

< 0.001

1.018 (1.003–1.033)

0.019

1.020 (1.005–1.034)

0.007

 Mechanical ventilation time

1.533 (1.341–1.798)

< 0.001

    

 AKI (yes/no)

28.350 (3.842–209.203)

0.001

    

 Stage of AKI

 

< 0.001

 

< 0.001

 

< 0.001

  Stage 1

5.859 (0.735–46.720)

0.095

2.424 (0.267–21.990)

0.431

2.218 (0.253–19.426)

0.472

  Stage 2

10.138 (1.162–88.457)

0.036

4.560 (0.478–43.545)

0.187

3.698 (0.385–35.548)

0.257

  Stage 3

165.053 (21.354–1275.729)

< 0.001

46.134 (5.436–391.525)

< 0.001

46.318 (5.666–378.663)

< 0.001

 Use of CRRT (yes/no)

23.756 (10.359–54.481)

0.001

    

 Use of PE/BA (yes/no)

11.527 (2.432–54.631)

0.002

    

 Use of ECMO (yes/no)

14.842 (1.757–125.357)

0.013

20.795 (1.620–266.917)

0.02

10.130 (0.900–113.958)

0.061

 Peak TB concentration

1.009 (1.005–1.012)

< 0.001

1.017 (1.002–1.032)

0.023

  

 Peak TB ≥121 μmol/l, (yes/no)

3.899 (2.220–6.847)

< 0.001

  

2.681 (1.119–6.425)

0.027

 Time to peak TB concentration

1.441 (1.277–1.626)

< 0.001

    

ICU stay time

1.268 (1.172–1.371)

< 0.001

    
  1. Model 1 was established by analysis of peak TB concentration; Model 2 was established by subgroup analysis of peak bilirubin concentration greater or less than 121.2 μmol/l
  2. ACC Aortic cross clamp, AKI Acute kidney injury, APACHEII Acute physiology and chronic health evaluation II, BA Bilirubin adsorption, CPB Cardiopulmonary bypass, CRRT Continuous renal replacement therapy, ECMO Extracorporeal membrane oxygenation, ICU Intensive care unit, MAP Mean arterial pressure, PE Plasma exchange, SCr Serum creatinine, TB Total bilirubin
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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