Patient population (n)
|
56
|
71
|
36
|
24
| | |
Demographic data
|
Age (y)
|
48.0 (16.5)
|
48.0 (15.0)
|
48.0 (13.5)
|
41.0 (8.3)
|
0.2
|
0.07
|
Sex, male (n)
|
31 (55.4%)
|
52 (73.2%)
|
24 (66.7%)
|
18 (75.0%)
|
0.03
|
0.1
|
Height (cm)
|
170.0 (12.8)
|
171.0 (7.0)
|
172.0 (10.5)
|
170.0 (13.0)
|
0.4
|
0.5
|
Weight (kg)
|
71.9 ± 10.2
|
78.0 ± 12.6
|
77.1 ± 14.4
|
77.8 ± 13.4
|
0.003
|
0.07
|
BMI (kg/m2)
|
25.5 ± 2.8
|
25.7 ± 5.6
|
26.4 ± 3.9
|
28.2 ± 3.7
|
0.3
|
0.2
|
Medical history
|
Diabetes (n)
|
2 (3.6%)
|
1 (1.4%)
|
2 (5.6%)
|
1 (4.2%)
|
0.9
|
0.7
|
Hypertension (n)
|
38 (67.9%)
|
46 (64.8%)
|
30 (83.3%)
|
23 (95.8%)
|
0.3
|
0.009
|
Chronic obstructive pulmonary disease (n)
|
1 (1.8%)
|
1 (1.4%)
|
0 (0.0%)
|
0 (0.0%)
|
0.5
|
0.8
|
Peripheral vascular disease (n)
|
4 (7.1%)
|
5 (7.0%)
|
4 (11.1%)
|
1 (4.2%)
|
0.9
|
0.8
|
Smoking (n)
|
17 (30.4%)
|
21 (29.6%)
|
13 (36.1%)
|
9 (37.5%)
|
0.7
|
0.8
|
Preoperative laboratory tests
|
Platelet (109/L)
|
195.5 (106.0)
|
191.0 (82.0)
|
191.0 (83.3)
|
177.0 (65.5)
|
0.1
|
0.2
|
Lymphocyte (109/L)
|
1.39 (0.75)
|
1.24 (0.81)
|
1.13 (0.59)
|
1.41 (0.99)
|
0.01
|
0.03
|
Monocyte (109/L)
|
0.70 (0.56)
|
0.67 (0.60)
|
0.89 (0.63)
|
0.92 (0.82)
|
0.03
|
0.03
|
Neutrophil (109/L)
|
7.39 ± 3.60
|
7.76 ± 3.41
|
8.97 ± 3.33
|
10.52 ± 3.76
|
0.04
|
0.001
|
Hyperlipidemia (n)
|
14 (25.0%)
|
16 (22.5%)
|
3 (8.3%)
|
9 (37.5%)
|
0.6
|
0.02
|
Retinol binding protein (mg/L)
|
27.6 (24.1)
|
27.9 (17.1)
|
21.2 (16.4)
|
37.3 (25.2)
|
0.7
|
0.02
|
Preoperative renal function
|
Dissection involving renal artery (n)
|
4 (7.1%)
|
6 (8.5%)
|
4 (11.1%)
|
5 (20.8%)
|
0.4
|
0.3
|
Preoperative SCr (μmol/L)
|
65.5 (31.0)
|
75.0 (24.4)
|
68.5 (36.2)
|
81.1 (47.9)
|
0.2
|
0.2
|
> 106 (n)
|
6 (10.7%)
|
10 (14.1%)
|
4 (11.1%)
|
7 (29.2%)
|
0.3
|
0.2
|
Surgical details
|
Involving the aortic arch (n)
|
50 (89.3%)
|
66 (93.0%)
|
35 (97.2%)
|
24 (100.0%)
|
0.1
|
0.2
|
Involving the descending aorta (n)
|
43 (76.8%)
|
59 (83.1%)
|
33 (91.7%)
|
23 (95.8%)
|
0.06
|
0.1
|
CPB duration (min)
|
188.0 (38.8)
|
201.0 (44.0)
|
222.0 (51.8)
|
235.0 (60.0)
|
< 0.001
|
< 0.001
|
DHCA or MHCA (n)
|
48 (85.7%)
|
65 (91.5%)
|
34 (94.4%)
|
23 (95.8%)
|
0.1
|
0.4
|
Aortic cross-clamp time (min)
|
94.5 (21.8)
|
99.0 (31.0)
|
96.0 (32.5)
|
110.0 (29.0)
|
0.02
|
0.02
|
Operation time (h)
|
7.0 (1.5)
|
8.0 (1.5)
|
8.5 (1.9)
|
9.0 (2.5)
|
< 0.001
|
< 0.001
|
Combined surgery
|
CABG (n)
|
1 (1.8%)
|
2 (2.8%)
|
0 (0.0%)
|
3 (12.5%)
|
0.5
|
0.04
|
Valvular surgery (n)
|
8 (14.3%)
|
7 (9.9%)
|
1 (2.8%)
|
0 (0.0%)
|
0.07
|
0.1
|
Outcomes
|
Renal replacement therapy (n)
|
0 (0.0%)
|
0 (0.0%)
|
0 (0.0%)
|
11 (45.8%)
|
0.03
|
< 0.001
|
Length of ICU stay (day)
|
5.0 (3.8)
|
5.0 (2.0)
|
5.0 (4.0)
|
12.0 (11.5)
|
0.02
|
< 0.001
|
> 7 d (n)
|
17 (30.4%)
|
16 (22.5%)
|
13 (36.1%)
|
22 (91.7%)
|
0.3
|
< 0.001
|
Intubation time (h)
|
19.0 (20.0)
|
24.0 (32.0)
|
40.5 (75.8)
|
147.5 (81.0)
|
< 0.001
|
< 0.001
|
> 5 d (n)
|
4 (7.1%)
|
4 (5.6%)
|
5 (13.9%)
|
17 (70.8%)
|
0.03
|
< 0.001
|
Redo surgery (n)
|
2 (3.6%)
|
2 (2.8%)
|
5 (13.9%)
|
6 (25.0%)
|
0.1
|
0.002
|
In-hospital mortality (n)
|
1 (1.8%)
|
1 (1.4%)
|
0 (0.0%)
|
7 (29.2%)
|
0.2
|
< 0.001
|