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Table 3 Cox proportional hazards analysis of prognostic factors in patients with cN1 disease

From: Preoperative identification of clinicopathological prognostic factors for relapse-free survival in clinical N1 non-small cell lung cancer: a retrospective single center-based study

 

Unfavorable vs. favorable

OS

RFS

HR

95% CI

P-value

HR

95% CI

P-value

Univariate analysis

 Sex

Female vs. male

1.075

0.502–2.305

0.8517

1.269

0.586–2.750

0.5455

 Age

≥70 vs. < 70 years

2.369

1.152–4.870

0.0190*

1.020

0.510–1.960

0.9543

 Histology

Adenocarcinoma vs. others

1.171

0.602–2.277

0.6419

1.265

0.635–2.520

0.5037

 Tumor size

> 30 vs. ≤30 mm

0.892

0.427–1.865

0.7622

1.066

0.495–2.296

0.8710

 CEA

≥5.0 vs. < 5.0 ng/mL

1.235

0.634–2.405

0.5348

2.901

1.374–6.127

0.0052*

 Primary tumor SUVmax

High vs. low

2.284

1.159–4.502

0.0171*

2.312

1.155–4.630

0.0180*

Multivariate analysis

 Sex

Female vs. male

1.315

0.556–3.276

0.5564

1.018

0.430–2.413

0.9669

 Age

≥70 vs. < 70 years

2.751

1.300–5.822

0.0081*

1.130

0.545–2.343

0.7419

 Histology

Adenocarcinoma vs. others

1.970

0.754–5.149

0.1668

1.353

0.575–3.181

0.4884

 Tumor size

> 30 vs. ≤30 mm

1.989

0.603–6.565

0.2589

0.523

0.186–1.475

0.2205

 CEA

≥5.0 vs. < 5.0 ng/mL

1.039

0.504–2.143

0.9170

2.376

1.056–5.348

0.0366*

 Primary tumor SUVmax

High vs. low

5.121

1.759–14.910

0.0027*

2.789

1.042–7.458

0.0410*

  1. HR Hazard ratio, CI Confidence interval. *P < 0.05
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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