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Table 3 Cox proportional hazards analysis of prognostic factors in patients with cN1 disease

From: Preoperative identification of clinicopathological prognostic factors for relapse-free survival in clinical N1 non-small cell lung cancer: a retrospective single center-based study

  Unfavorable vs. favorable OS RFS
HR 95% CI P-value HR 95% CI P-value
Univariate analysis
 Sex Female vs. male 1.075 0.502–2.305 0.8517 1.269 0.586–2.750 0.5455
 Age ≥70 vs. < 70 years 2.369 1.152–4.870 0.0190* 1.020 0.510–1.960 0.9543
 Histology Adenocarcinoma vs. others 1.171 0.602–2.277 0.6419 1.265 0.635–2.520 0.5037
 Tumor size > 30 vs. ≤30 mm 0.892 0.427–1.865 0.7622 1.066 0.495–2.296 0.8710
 CEA ≥5.0 vs. < 5.0 ng/mL 1.235 0.634–2.405 0.5348 2.901 1.374–6.127 0.0052*
 Primary tumor SUVmax High vs. low 2.284 1.159–4.502 0.0171* 2.312 1.155–4.630 0.0180*
Multivariate analysis
 Sex Female vs. male 1.315 0.556–3.276 0.5564 1.018 0.430–2.413 0.9669
 Age ≥70 vs. < 70 years 2.751 1.300–5.822 0.0081* 1.130 0.545–2.343 0.7419
 Histology Adenocarcinoma vs. others 1.970 0.754–5.149 0.1668 1.353 0.575–3.181 0.4884
 Tumor size > 30 vs. ≤30 mm 1.989 0.603–6.565 0.2589 0.523 0.186–1.475 0.2205
 CEA ≥5.0 vs. < 5.0 ng/mL 1.039 0.504–2.143 0.9170 2.376 1.056–5.348 0.0366*
 Primary tumor SUVmax High vs. low 5.121 1.759–14.910 0.0027* 2.789 1.042–7.458 0.0410*
  1. HR Hazard ratio, CI Confidence interval. *P < 0.05