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Table 1 The basic characteristics of enrolled studies

From: Meta-analysis of association between CT-based features and tumor spread through air spaces in lung adenocarcinoma

author year region N(M/F) year STAS(+/−) subtype stage Lobectomy/sublobar Resection NOS CT-based features
Kadota et al. [4] 2015 Japan 411 (164/247) 68 155/256 ADC I 291/120 7 part-solid nodule.
Shiono et al. [15] 2016 Japan 318 (149/169) 70 47/271 ADC I 202/116 5 pure solid nodule.
Dai et al. [10] 2017 China 383 (178/205) 60 116/267 ADC I 364/19 6 radiological tumor size>2 cm.
Masai et al. [16] 2017 Japan 508 (248/260) 66 76/432 ADC I 0/508 7 part-solid nodule.
Toyokawa et al. [17] 2018 Japan 327 (153/174) 69 191/136 ADC I-IV 235/84 7 radiological tumor size>2 cm,pure solid nodule,part-solid nodule.
de Margerie-Mellon et al. [18] 2018 USA 80 (27/53) 68 40/40 ADC NA NA 6 radiological tumor size>2 cm, part-solid nodule.
Kim et al. [19] 2018 Republic of Korea 276 (129/147) 59 92/184 ADC I-III 226/50 6 pure solid nodule, part-solid nodule.
Toyokawa et al. [20] 2018 Japan 82 (40/42) 71 31/51 ADC I 0/82 7 radiological tumor size>2.0 cm.