Table 1 Pre-determined primary and secondary endpoints extracted from eligible full-text articles
Primary endpoints | Secondary endpoints | |||||
|---|---|---|---|---|---|---|
Mortality | Reoperations | Transvalvular gradient | Valvular function | Valvular characteristics | Histological commentary | Adverse events |
30-day | 30-day | Overall | Insufficiency | Diameter | Fibroproliferation | Infective endocarditis OR freedom from infective endocarditis |
1-year | 1-year | Â | Stenosis | Area | Recellularization | Valve thrombosis OR freedom from valve thrombosis |
Overall rate OR freedom from mortality | Overall rate OR freedom from reoperations | Â | Explantation rate OR freedom from explantation | Calcification | Antibody/humoral immune response | Â |
| Â | Time to reoperation | Â | Rate of dysfunction OR freedom from dysfunction | Cusp mobility | Â | Â |
| Â | Â | Â | Failure rate OR freedom from failure | Cusp retraction | Â | Â |