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Table 1 Perioperative Clinical Profiles

From: Perioperative risk factors predict one-year mortality in patients with acute type-A aortic dissection

Variables Total Alive Death HR 95% CI p Value
Preoperative
 Number (n) 121 109 12   
 Age (year) 46.6 ± 10.4 45.7 ± 9.9 55.2 ± 11.1 1.0986 1.0318–1.1697 0.0033
 Males, n (%) 93 (77) 84 (77) 9 (75) 0.8957 0.2425–3.3087 0.8688
 BMI (kg/M2) 25.9 ± 3.2 25.9 ± 3.3 25.3 ± 2.7 0.9375 0.7820–1.1239 0.4852
 History of smoking, n (%) 63 (52) 57 (52) 6 (50) 0.9001 0.2903–2.7912 0.8554
 History of hypertension, n (%) 86 (71) 77 (71) 9 (75) 1.2185 0.3299–4.5012 0.7669
 Time from onset of symptoms to surgery (d) 2.00 (1.00–5.00) 2.00 (1.00–5.00) 1.00 (0.95–2.25) 0.7173 0.4982–1.0328 0.0740
 Aortic diameter (mm) 47.6 ± 8.2 47.2 ± 7.9 50.7 ± 10.0 1.0416 0.9816–1.1053 0.1785
 Hear rate (beats/min) 77 ± 15 76 ± 15 78 ± 15 1.0103 0.9745–1.0474 0.5779
 SBP (mm Hg) 114 ± 18 113 ± 18 115 ± 19 1.0044 0.9736–1.0362 0.7822
 DBP (mm Hg) 57 ± 12 56 ± 12 59 ± 16 1.0277 0.9806–1.0771 0.2541
 LVEF (%) 63 ± 9 62 ± 9 64 ± 6 1.0236 0.9415–1.1130 0.5843
 LVEDd (mm) 51 ± 8 52 ± 8 49 ± 7 0.9412 0.8560–1.0349 0.2106
 HB (g/L) 12.7 ± 1.4 12.8 ± 1.4 12.2 ± 0.9 0.7723 0.5246–1.1369 0.1903
 PLC (109/L) 175 ± 69 180 ± 68 132 ± 52 0.9897 0.9796–0.9998 0.0455
 WBC (109/L) 9.5 ± 3.5 9.5 ± 3.5 9.3 ± 2.6 0.9909 0.8374–1.1726 0.9156
 LAC (mmol/L) 1.00 (0.80–1.30) 0.90 (0.80–1.30) 1.55 (1.00–2.17) 1.4802 1.1239–1.9493 0.0052
 EuroSCOREII 5.00 (5.00–6.00) 5.00 (5.00–5.00) 5.50 (5.00–6.25) 1.8392 1.0416–3.2476 0.0357
Intraoperative
 B + S n (%) 66 (54.55%) 61 (55.96%) 5 (41.67%) 0.5943 0.1886–1.8726 0.3742
 A + S n (%) 55 (45.45%) 48 (44.04%) 7 (58.33%) 1.6826 0.5340–5.3017 0.3742
 Duration of surgery (min) 451 ± 102 443 ± 97 520 ± 133 1.0062 1.0013–1.0111 0.0126
 Duration of CPB (min) 198 ± 53 196 ± 51 213 ± 69 1.0045 0.9959–1.0131 0.3045
 Cross clamp time (min) 115 ± 38 114 ± 39 120 ± 32 1.0034 0.9900–1.017 0.6212
 Lowest rectal temperature (°C) 25.8 ± 2.1 25.8 ± 2.1 25.5 ± 2.2 0.9176 0.6861–1.2272 0.5622
 Allogeneic Red blood cells (units) 2.00 (0.00–4.00) 2.00 (0.00–4.00) 4.00 (1.50–6.25) 1.2395 1.0465–1.4682 0.0129
 Blood transfusion > 2000 mL 18 (14.88) 13 (11.93) 5 (41.67) 4.8038 1.5229–15.1534 0.0074
End of surgery
 Heart rate (beats/min) 95 ± 17 94 ± 16 105 ± 17 1.0315 1.0065–1.0572 0.0132
 SBP (mmHg) 117 ± 15 118 ± 14 114 ± 17 0.9805 0.9420–1.0206 0.335
 DBP (mmHg) 62 ± 11 62 ± 10 61 ± 15 0.9917 1.0084–1.0481 0.7680
 HB (g/L) 10.1 ± 1.9 10.1 ± 1.8 10.5 ± 2.5 1.0806 0.8150–1.4327 0.5901
 PLC (109/L) 109 ± 52 112 ± 54 84 ± 29 0.9879 0.9743–1.0017 0.0855
 WBC (109/L) 11.2 ± 4.4 11.3 ± 4.4 10.0 ± 3.5 0.9330 0.8005–1.0874 0.3748
 LAC (mmol/L) 3.65 (2.00–5.75) 3.50 (1.90–5.45) 5.80 (4.85–8.90) 1.2738 1.1005–1.4744 0.0012
 OI < 200 mmHg, n (%) 64 (52.89) 54 (49.5) 10 (83.3) 4.5814 1.0037–20.9106 0.0494
Postoperative
 Postoperative LVEF (%) 61 ± 8 61 ± 7 54 ± 14 0.9049 0.8421–0.9723 0.0064
 Serum creatinine (μmol/L) 109 ± 52 104 ± 44 163 ± 80 1.0146 1.0067–1.0225 0.0003
 Neurological deficits, n (%) 12 (9.92%) 9 (8.26%) 3 (25.00%) 3.4885 0.9436–12.8974 0.0611
 prolonged mechanical ventilation n (%) 35 (28.93%) 27 (24.77%) 8 (66.67%) 5.6310 1.6932–18.7263 0.0048
 Reexploration for bleeding or debridement, n (%) 11 (9.09%) 9 (8.26%) 2 (16.67%) 1.0932 0.1410–8.4735 0.9321
 Tracheotomy n (%) 10 (8.26%) 7 (6.42%) 3 (25.00%) 4.4911 1.2135–16.6210 0.0245
 CRRT n (%) 5 (4.13%) 3 (2.75%) 2 (16.67%) 5.8043 1.2696–26.5370 0.0233
  1. Abbreviations: A + S ascending aorta replacement + Sun’s procedure, B + S Bentall + Sun’s procedure, BMI body mass index, CI confidence interval, CPB cardiopulmonary bypass, CRRT continuous renal replacement therapy, DBP diastolic blood pressure, HB hemoglobin, HR hazard ratio, LAC lactate, LVEDd left ventricular end-diastolic dimension, LVEF left ventricular ejection fraction, OI oxygenation index, PLC preoperative platelet count, SBP systolic blood pressure, WBC white blood cells