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Table 3 Risk of AKI after CABG according to oral hypoglycemic and insulin treatment, stratified by preoperative renal function

From: The impact of diabetes mellitus on acute kidney injury after coronary artery bypass grafting

 

All

No-DM group

DM-oral group

DM-insulin group

eGFR ≥60 mL/min/1.73 m2

 No. of patients

3456

2484

558

414

 No. of AKI(%)

358(10.4)

205(8.3)

63(11.3)

90(21.7)

Risk of AKI

 

OR (95% CI)

1

1.69

3.7

(crude analysis)

  

1.25–2.28

2.81–4.86

Risk of AKI

 

1

1.2

4.35

(multivariable adjusteda)

  

0.89–1.66

2.79–6.38

eGFR 45–60 mL/min/1.73 m2

 No. of patients

644

461

89

94

 No. of AKI(%)

150(23.3)

96(20.8)

23(25.8)

31(32.8)

Risk of AKI

 

OR (95% CI)

1

1.33

1.87

(crude analysis)

  

0.78–2.24

1.15–3.04

Risk of AKI

 

1

1.18

2.9

(multivariable adjusteda)

  

0.64–2.07

2.17–5.31

eGFR 15–45 mL/min/1.73 m2

 No. of patients

225

122

59

44

 No. of AKI(%)

83(36.9)

37(30.3)

22(37.3)

24(54.5)

Risk of AKI

 

OR (95% CI)

1

1.37

2.75

(crude analysis)

  

0.71–2.63

1.36–5.60

Risk of AKI

 

1

1.18

4.02

(multivariable adjusteda)

  

0.59–2.17

2.44–6.59

  1. AKI was defined as increase creatinine ×1.5 from baseline or increase of > 0.3 mg/dL within 48 h
  2. a The final multivariable model included all variables in Table 1 except EuroSCOREII