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Table 4 Risk of AKI after CABG according to oral hypoglycemic and insulin treatment, stratified by preoperative cardiac function

From: The impact of diabetes mellitus on acute kidney injury after coronary artery bypass grafting

 

All

No-DM group

DM-oral group

DM-insulin group

LVEF> 0.50

 No. of patients

3140

2248

513

379

 No. of AKI(%)

350(11.1)

203(9.0)

63(12.3)

84(22.2)

Risk of AKI

 

OR (95% CI)

1

1.41

2.87

(crude analysis)

  

1.04–1.91

2.16–3.80

Risk of AKI

 

1

1.09

4.11

(multivariable adjusteda)

  

0.79–1.31

2.97–5.05

LVEF 0.30–0.50

 No. of patients

1066

742

173

151

 No. of AKI(%)

201(18.9)

114(15.4)

38(22.0)

49(32.5)

Risk of AKI

 

OR (95% CI)

1

1.55

2.65

(crude analysis)

  

1.03–2.34

1.78–3.93

Risk of AKI

 

1

1.18

3.47

(multivariable adjusted)

  

0.67–1.84

2.11–4.80

LVEF< 0.30

 No. of patients

119

77

20

22

 No. of AKI(%)

40(33.6)

21(27.3)

7(35.0)

12(54.5)

Risk of AKI

 

OR (95% CI)

1

1.44

3.2

(crude analysis)

  

0.50–4.09

1.20–8.51

Risk of AKI

 

1

1.15

4.06

(multivariable adjusteda)

  

0.34–3.57

2.19–9.83

  1. AKI was defined as increase creatinine ×1.5 from baseline or increase of > 0.3 mg/dL within 48 h
  2. a The final multivariable model included all variables in Table 1 except EuroSCOREII