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Table 3 Demographics and Perioperative Characteristics of HTx Recipients Stratified by RRT

From: Incidence, risk factors and clinical outcomes of acute kidney injury after heart transplantation: a retrospective single center study

  Non-AKI without RRT
(n = 62)
AKI without RRT (n = 17) AKI with RRT
(n = 16)
P value
Demographic data
 Age, years 53.87 ± 11.94 52.24 ± 14.63 58.19 ± 7.77 0.597
  < 60 36(58.06) 10(58.82) 9(56.25) 0.988
  ≥ 60 26(41.94) 7(41.18) 7(43.75)
 Sex, men, n (%) 5(80.65) 17(100) 14(87.50) 0.135
 BMI (kg/m2) 24.14 ± 3.51 25.11 ± 4.52 25.47 ± 4.23 0.368
 History of alcohol 21(33.87) 2(11.76) 6(37.50) 0.176
 History of smoking 40(64.52) 13(76.47) 10(62.50) 0.616
 Hypertension 22(35.48) 9(52.94) 8(50.00) 0.318
 Diabetes mellitus 20(32.26) 6(35.29) 8(50.00) 0.422
 Chronic kidney disease 10(16.13) 3(16.13) 7(43.75) 0.052
Pretransplant characteristics
 DCM 30(48.39) 5(29.41) 3(18.75) 0.062
 CAD 14(22.58) 5(29.41) 8(50.00) 0.097
 Valve disease 10(16.13) 2(11.76) 3(18.75) 0.854
 Pre-PCI 4(6.45) 5(29.41) 2(12.50) 0.033*
 ICD implantation 3(4.84) 0(0) 0(0) 0.442
 LVAD implantation 0(0) 1(5.88) 0(0) 0.098
 Cardiac tumor 1(1.61) 0(0) 0(0) 0.764
 EF pre-HTx (%) 27(22,30) 28(25,30) 28.5(24.5,33.5) 0.571
 Creatinine (mg/dL) 1.14(0.95,1.27) 1.14(1.00,1.19) 1.25(1.04,1.51) 0.244
 GFR (ml/min/1.73 m2) 38.05(29.68,46.23) 39.18(35.39,47.80) 37.36(24.10,40.43) 0.183
  < 30 16(25.81) 2(11.76) 7(43.75) 0.189
 30–59 40(64.52) 12(70.59) 9(56.25)
  ≥ 60 6(9.68) 3(17.65) 0(0)
Intraoperative characteristics
 CPB duration (min) 209(180,240) 210(210,240) 269(232.5297.5) 0.0088*
 Blood transfusion (ml) 1440(1000,2100) 1440(1000,1812) 1500(1300,2625) 0.499
 Infusion (ml) 1800(1300,2220) 1980(1400,2950) 2055(1285,3025) 0.275
 Blood loss (ml) 1000(1000,2000) 1000(1000,2500) 2200(1300,3350) 0.0298*
 Urine volume (ml) 2000(1300,2700) 1500(1000,2000) 1100(710,2000) 0.0021*
 IABP/ECMO 1(1.61) 0(0) 5(31.25) <.0001*
Postoperative characteristics
 Urine volume
  1st Day after operation 2200(2030,2795) 2470(2100,3010) 1597.5(521,2214) 0.0016*
  2nd Day after operation 2197.5(1875) 2130(1800,2465) 1253.5(145,2087.5) 0.0020*
  3rd Day after operation 2180(2005,2615) 2090(2000,2265) 1365(75,2112.5) 0.0002*
  Mechanical ventilation (min) 1020(780,2080) 960(783,1380) 3090(1550,6141) 0.0033*
  Time from operation to discharge (days) 25(22,30) 28(24,34) 38(24.5,64) 0.029*
  Death 7(11.29) 0(0) 8(50.00) 0.0001*
  Mortality in hospital 4(6.45) 0(0) 7(43.75) <.0001*
  Death within 1 year 3(4.84) 0(0) 0(0) 0.438
  Follow-up days 658.5(382,1162) 954(489,2336) 261(24.5736.5) 0.0028*
  1. * P < 0.05; ANOVA was applied to the BMI variable because of its normal distribution. The Kruskal-Wallis test was used to compare other variables