Clinical variables | Non-aPRP Group(n = 388) | aPRP Group(n = 272) | P Value |
---|---|---|---|
Age (year) | 49.29 ± 10.60 | 47.52 ± 9.77 | 0.030 |
Males, n (%) | 305 (78.4) | 230 (84.6) | 0.067 |
Height (cm) | 172.05 ± 7.51 | 171.49 ± 8.02 | 0.359 |
Weight (kg) | 77.02 ± 13.16 | 78.8 ± 13.20 | 0.073 |
BMI (kg/M2) | 25.97 ± 3.75 | 26.75 ± 3.70 | 0.009 |
History of smoking, n (%) | 137 (35.2) | 120 (44.1) | 0.023 |
History of hypertension, n (%) | 294 (75.8) | 199 (73.2) | 0.448 |
History of DM, n (%) | 18 (4.6) | 13 (4.8) | 0.933 |
Time from onset of symptoms to surgery (d) | 2 (1,4) | 2 (1, 4) | 0.768 |
preoperative | |||
LVEF (%) | 60.22 ± 6.52 | 60.58 ± 6.302 | 0.490 |
LVEDd (mm) | 50.76 ± 8.71 | 49.888 ± 7.8517 | 0.195 |
EuroSCORE | 5 (4.5,5) | 5 (5,5) | 0.408 |
HR (beats/min) | 80 ± 15 | 80 ± 15 | 0.334 |
MBP (mm Hg) | 89 ± 18 | 85 ± 22 | 0.014 |
Hb(g/L) | 12.68 ± 2.63 | 13.91 ± 4.14 | 0.001 |
WBC (109/L) | 10.91 ± 4.11 | 11.38 ± 3.72 | 0.135 |
PLC(109 /L) | 151 ± 76 | 171 ± 64 | 0.001 |
LAC (mmol/L) | 1.52 ± 0.95 | 1.56 ± 0.87 | 0.549 |
SCr (umol/L) | 102.9 ± 53.1 | 82.6 ± 37.6 | < 0.001 |
PT (second) | 12.74 ± 2.29 | 12.81 ± 2.06 | 0.727 |
PTA(100%) | 87.03 ± 14.44 | 84.67 ± 14.67 | 0.128 |
APTT (second) | 32.83 ± 11.51 | 31.70 ± 6.76 | 0.211 |
FIB(g/L) | 3.30 ± 1.49 | 3.21 ± 1.56 | 0.571 |
FDP (mg/L) | 18.65 (9.01,31.45) | 19.2 (10.2,35.65) | 0.329 |
D-D (ug/L) | 1581 (850, 2976) | 1836 (808, 2719) | 0.660 |
INR | 1.09 (1.03,1.18) | 1.11 (1.04,1.19) | 0.192 |
Intraoperative | |||
With CABG | 13 (5.2) | 16 (6.5) | 0.537 |
Duration of surgery (min) | 465 ± 99 | 492 ± 105 | 0.001 |
Duration of CPB (min) | 271.49 ± 172.64 | 281.27 ± 152.09 | 0.453 |
Duration of Aortic cross-clamping (min) | 92.97 ± 56.01 | 86.95 ± 54.77 | 0.171 |
Lowest rectal temperature (°C) | 25.21 ± 2.13 | 25.21 ± 1.79 | 0.966 |
Lowest nasopharyngeal temperature (°C) | 22.46 ± 6.02 | 22.91 ± 6.60 | 0.363 |
Intravenous crystalloid (mL) | 2153 ± 887 | 2354 ± 1133 | 0.015 |
Allogeneic Red blood cells (units) | 0 (0, 4) | 0 (0, 3) | 0.012 |
Allogeneic blood Plasma (mL) | 200 (0, 600) | 0 (0,400) | 0.001 |
aBlood product transfused (ml) | 520 (0,1040) | 375 (0,975) | 0.014 |
Urine volume during surgery (mL) | 1591 ± 1073 | 1643 ± 863 | 0.503 |
Postoperative | |||
LVEF (%) | 59.68 ± 7.04 | 59.59 ± 6.57 | 0.870 |
HR (beats/min) | 93 ± 17 | 94 ± 16 | 0.384 |
MBP (mmHg) | 88 ± 19 | 86 ± 20 | 0.20 |
Hb(g/L) | 10.23 ± 1.86 | 10.42 ± 1.57 | 0.545 |
WBC (109/L) | 11.48 ± 4.86 | 12.15 ± 4.57 | 0.20 |
PLC(109 /L) | 106 ± 51 | 97 ± 62 | 0.14 |
LAC (mmol/L) | 2.79 ± 3.12 | 3.97 ± 3.93 | <0.001 |
PT (second) | 13.77 ± 4.45 | 13.18 ± 2.39 | 0.080 |
PTA(100%) | 82.81 ± 15.72 | 81.56 ± 14.86 | 0.442 |
APTT (second) | 32.63 ± 7.13 | 33.10 ± 12.04 | 0.628 |
FIB(g/L) | 3.34 ± 1.43 | 3.39 ± 1.97 | 0.731 |
FDP (mg/L) | 19 (9.17,32.4) | 17.56 (9.52,35.67) | 0.929 |
D-D (ug/L) | 1963 (855,3046) | 1619 (815,2841) | 0.510 |
INR | 1.12 (1.04,1.24) | 1.14 (1.06,1.24) | 0.323 |
SCr (umol/L) | 118.58 ± 72.59 | 105.89 ± 51.50 | 0.011 |
Postoperative 24 h | |||
SCr (umol/L) | 133.1 ± 91.8 | 115.2 ± 66.6 | 0.005 |
Seroma volume of drainage (mL) | 1472 ± 667 | 1539 ± 820 | 0.263 |
Postoperative 48 h | |||
SCr (umol/L) | 136.1 ± 106.3 | 122.3 ± 98.2 | 0.102 |
Postoperative 72 h | |||
SCr (umol/L) | 113.4 ± 93.7 | 110.1 ± 77.5 | 0.737 |