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Table 2 In vivo effects of Sfrp1 on CVF, Col-1 levels and apoptosis rate

From: Sfrp1 protects against acute myocardial ischemia (AMI) injury in aged mice by inhibiting the Wnt/β-catenin signaling pathway

 

Control

M3

M3 + Sfrp1

M7

M7 + Sfrp1

CVF levels

1.00 ± 0.12

1.69 ± 0.27**

1.14 ± 0.15#

2.74 ± 0.41**

1.92 ± 0.47**&&

Col-1 levels

1.00 ± 0.08

1.62 ± 0.25**

1.22 ± 0.19#

2.88 ± 0.26**

2.01 ± 0.26**&&

Apoptosis rate (%)

9.23 ± 1.72

32.15 ± 3.43**

21.76 ± 2.22**##

47.33 ± 5.12**

23.34 ± 2.86**&&

  1. **P < 0.01, compared to control group; #P < 0.05, compared to M3 group; &&P < 0.01, compared to M7 group
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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