Characteristics
|
SHR
|
P
|
SHR
|
P
|
---|
LNR classification
|
LNR1
|
1(Reference)
| | | |
LNR2
|
1.56 (1.47–1.67)
|
< 0.001
| | |
LNR3
|
2.54 (2.30–2.80)
|
< 0.001
| | |
N stage
|
N1
| | |
1 (Reference)
| |
N2
| | |
1.54 (1.45–1.63)
|
< 0.001
|
N3
| | |
2.81 (2.32–3.41)
|
< 0.001
|
Sex
|
Female
|
1(Reference)
| |
1(Reference)
| |
Male
|
1.23 (1.16–1.30)
|
< 0.001
|
1.21 (1.134–1.29)
|
< 0.001
|
Race
|
White
|
1(Reference)
| |
1(Reference)
| |
Black
|
0.94 (0.85–1.05)
|
0.262
|
0.97 (0.87–1.07)
|
0.506
|
Others
|
0.90 (0.81–1.00)
|
0.040
|
0.88 (0.79–0.98)
|
0.020
|
Primary site
|
Upper lobe
|
1(Reference)
| |
1(Reference)
| |
Lowerlobe
|
1.08 (1.01–1.15)
|
0.018
|
1.11 (1.04–1.18)
|
0.001
|
Mainbronchus
|
1.20 (0.96–1.49)
|
0.103
|
1.21 (0.98–1.51)
|
0.083
|
Middlelobe
|
0.93 (0.81–1.06)
|
0.290
|
1.03 (0.91–1.18)
|
0.625
|
Overlapping/NOS
|
1.28 (1.10–1.49)
|
0.001
|
1.30 (1.12–1.52)
|
< 0.001
|
Grade
|
I/II
|
1(Reference)
| |
1(Reference)
| |
III/IV
|
1.23 (1.16–1.31)
|
< 0.001
|
1.25 (1.18–1.33)
|
< 0.001
|
Histology
|
Adenocarcinoma
|
1(Reference)
| |
1(Reference)
| |
Squamous
|
0.92 (0.86–0.99)
| |
0.91 (0.84–0.97)
|
0.008
|
Others
|
1.15 (1.05–1.25)
|
0.002
|
1.14 (1.04–1.24)
|
0.003
|
T stage
| |
0.030
| | |
T1
|
1(Reference)
| | | |
T2
|
1.32 (1.23–1.412)
|
< 0.001
|
1.29 (1.199–1.38)
|
< 0.001
|
T3
|
1.85 (1.62–2.12)
|
< 0.001
|
1.78 (1.56–2.04)
|
< 0.001
|
T4
|
1.82 (1.64–2.01)
|
< 0.001
|
1.82 (1.64–2.01)
|
< 0.001
|
- LNR Lymph node ratio, SHR sub-distribution hazards ratio