| study population | heparin (H) | argatroban (A) | H vs. A p-value | switched (S) | H vs. S p-value |
---|---|---|---|---|---|---|
number | 215 100% (215/215) | 143 66.5% total (143/215) | 43 20% total (43/215) | Â | 29 13.5% total (29/215) | Â |
postoperative bleeding complication before initiation of anticoagulation | 14.4% (31/215) | 7.7% group (11/143) | 32.5% group (14/43) | Â | 20.7% group (6/29) | Â |
5.1% total (11/215) | 6.5% total (14/215) | 2.8% total (6/215) | ||||
postoperative bleeding complication after initiation of anticoagulation | 12.1% (26/215) | 9.8% group (14/143) | 14.0% group (6/43) | n.s. (0.413) | 20.7% group (6/29) | n.s. (0.113) |
6.5% total (14/215) | 2.8% total (6/215) | 2.8% total (6/215) | ||||
postoperative bleeding complication total | 26.5% (57/215) | 17.5% group (25/143) | 46.5% group (20/43) | < 0.001 | 41.4% group (12/29) | 0.011 |
11.6% total (25/215) | 9.3% total (20/215) | 5.6% total (12/215) |