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Table 5 Logistic regression analysis argatroban vs. heparin (n = 186)

From: Bleeding complications after cardiac surgery, before anticoagulation start and then with argatroban or heparin in the early postoperative setting

Model

Bleeding complications

OR (95% CI)

p-value

Argatroban crude

4.1 (2.0–8.6)

< 0.001

 Primary model confounder before argatroban

  argatroban adjusted preoperative hemoglobin, operation time, SAPS score, pTTmax

2.2 (0.9–5.1)

0.06

Sensitivity analysis

 Preoperative confounder

  argatroban adjusted preoperative hemoglobin, quick-value, operation time, SAPS score, pTTmax

2.2 (0.9–5.2)

0.06

 Postoperative confounder

  argatroban adjusted preoperative hemoglobin, operation time, SAPS score, pTTmax, liver cell damage, MELDmax, Bilimax

2.1 (0.8–5.2)

0.11

  1. Values reaching significance are merked bold