Table 1 Clinical characteristics of patients with AAAD
From: Preoperative uric acid predicts in-hospital death in patients with acute type a aortic dissection
Variable | All patients | Survivor | Non-survivor | p value |
|---|---|---|---|---|
(n = 186) | (n = 146) | (n = 40) | ||
Demographics | ||||
Age (years) | 50 ± 12 | 49 ± 12 | 55 ± 13 | 0.016 |
Male, n (%) | 149 (80%) | 118 (81%) | 31 (78%) | 0.641 |
Medical histories, n (%) | ||||
Hypertension | 105 (56%) | 80 (55%) | 25 (63%) | 0.384 |
Diabetes | 6 (3%) | 5 (3%) | 1 (3%) | 1 |
CKD | 7 (4%) | 7 (5%) | 0 (0%) | 0.349 |
Prior aortic stent implant | 9 (5%) | 8 (5%) | 1 (3%) | 0.687 |
Prior cardiac surgery | 3 (2%) | 3 (2%) | 0 (0%) | 1 |
Smoker | 72 (39%) | 61 (42%) | 11 (28%) | 0.1 |
Clinical presentation | ||||
Onset to operation time (hours) | 26 (17–39) | 28 (19–42) | 20 (14–32) | 0.011 |
Systolic blood pressure (mmHg) | 129 ± 30 | 129 ± 29 | 127 ± 32 | 0.7 |
Diastolic blood pressure (mmHg) | 72 ± 19 | 72 ± 19 | 72 ± 22 | 0.949 |
Heart rate (beats/min) | 80 (68–91) | 80 (69–91) | 79 (66–88) | 0.763 |
Ascending aorta diameter (mm) | 42 (40–50) | 42 (39–50) | 44 (41–48) | 0.231 |
Entry tears≥2, n (%) | 14 (8%) | 12 (8%) | 2 (5%) | 0.738 |
Laboratory tests on admission | ||||
UA (umol/L) | 386 ± 118 | 371 ± 111 | 446 ± 123 | < 0.001 |
Creatinine (umol/L) | 85 (69–117) | 84 (68–108) | 111 (77–142) | 0.004 |
BUN (mmol/L) | 6.80 (5.40–8.16) | 6.66 (5.27–8.00) | 7.19 (6.31–9.26) | 0.048 |
D-dimer (ug/mL FEU) | 8.7 (3.8–18.2) | 7.6 (3.5–16.0) | 17.9 (7.8–38.2) | < 0.001 |
Fibrinogen (g/L) | 2.18 (1.51–3.03) | 2.36 (1.67–3.10) | 1.76 (1.16–2.54) | 0.002 |
Platelet (109/L) | 166 (134–198) | 171 (139–202) | 153 (115–176) | 0.005 |
WBC (109/L) | 13.4 (10.7–16.0) | 13.2 (10.6–15.7) | 14.0 (10.9–16.9) | 0.134 |
Organ ischemia, n (%) | ||||
Brain | 10 (5%) | 7 (5%) | 3 (8%) | 0.450 |
Coronary artery involvement | 37 (20%) | 27 (18%) | 10 (25%) | 0.361 |
Lower limb | 45 (24%) | 31 (21%) | 14 (35%) | 0.072 |
eGFR< 60 ml/min/1.73 m2 | 49 (26%) | 31 (21%) | 18 (45%) | 0.003 |
Operation profiles | ||||
Extent of aortic replacement, n (%) | ||||
Total arch replacement | 106 (57%) | 76 (52%) | 30 (75%) | 0.009 |
Hemiarch replacement | 18 (10%) | 15 (10%) | 3 (8%) | 0.823 |
Ascending aortic replacement | 62 (33%) | 55 (38%) | 7 (17%) | 0.016 |
Bentall, n (%) | 63 (34%) | 50 (34%) | 13 (33%) | 0.836 |
Operation time (min) | 424 (354–520) | 406 (343–475) | 540 (455–649) | < 0.001 |
CPB time (min) | 200 (167–242) | 195 (162–227) | 238 (198–333) | < 0.001 |
ACC time (min) | 146 (121–187) | 141 (119–179) | 166 (138–208) | 0.012 |
HCA time (min) | 31 (0–41) | 30 (0–40) | 36 (29–46) | 0.001 |