Preoperative uric acid predicts in-hospital death in patients with acute type a aortic dissection

Table 2 Univariate analysis for in-hospital mortality

Clinical variables	OR (95% CI)	p value
Age (year)	1.040 (1.010–1.072)	0.01
Male	0.817 (0.350–1.910)	0.641
Hypertension	1.375 (0.670–2.820)	0.385
Diabetes	0.723 (0.082–6.372)	0.77
Prior aortic stent implant	0.442 (0.054–3.645)	0.448
Smoker	0.529 (0.245–1.139)	0.104
Onset to operation time (h)	0.988 (0.974–1.002)	0.095
Systolic blood pressure (mmHg)	0.998 (0.986–1.010)	0.699
Diastolic blood pressure (mmHg)	1.001 (0.983–1.019)	0.949
Heart rate (beat/min)	0.998 (0.980–1.017)	0.871
Ascending aorta diameter (mm)	1.004 (0.968–1.042)	0.815
Entry tears≥2	0.588 (0.126–2.741)	0.499
UA (umol/L)	1.005 (1.002–1.009)	0.001
Creatinine (umol/L)	1.000 (0.997–1.002)	0.965
BUN (mmol/L)	1.018 (0.939–1.103)	0.67
D-dimer (ug/mL FEU)	1.031 (1.015–1.048)	< 0.001
Fibrinogen (g/L)	0.653 (0.469–0.909)	0.012
Platelet (10⁹/L)	0.988 (0.980–0.996)	0.004
WBC (10⁹/L)	1.054 (0.978–1.135)	0.168
Brain ischemia	1.610 (0.397–6.531)	0.505
Coronary artery involvement	1.469 (0.641–3.365)	0.363
Lower limb ischemia	1.998 (0.933–4.276)	0.075
eGFR< 60 ml/min/1.73 m2	3.035 (1.450–6.352)	0.003
Extent of aortic replacement*	0.564 (0.363–0.876)	0.011
Bentall	0.924 (0.439–1.947)	0.836
Operation time (min)	1.010 (1.007–1.014)	< 0.001
CPB time (min)	1.011 (1.006–1.016)	< 0.001
ACC time (min)	1.007 (1.001–1.013)	0.013
HCA time (min)	1.034 (1.015–1.053)	< 0.001

The bold values indicate statistical significance
eGFR estimated glomerular filtration rate, UA uric acid, BUN blood urea nitrogen, WBC white blood cell count, CPB cardiopulmonary bypass, ACC aortic cross-clamping, HCA hypothermic circulatory arrest
*Categorical variable, total arch replacement was defined as “1”, hemiarch replacement was defined as “2”, ascending aortic replacement was defined as “3”

ISSN: 1749-8090