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Table 1 Baseline characteristics of patients with AADA and hypoxemia within 24 h after surgery: pre-PSM

From: Effects of inhaled nitric oxide for postoperative hypoxemia in acute type A aortic dissection: a retrospective observational study

VariableControl (N = 136)iNO treatment (N = 40)p-value
Age, y50.4 ± 11.049.9 ± 11.20.789
Men110 (80.9)31 (77.5)0.638
BMI26.5 ± 2.726.3 ± 2.90.707
Comorbidity
 Hypertension96 (70.6)32 (80.0)0.240
 Diabetes2 (1.5)2 (5.0)0.476
 COPD3 (2.2)1 (2.5)1.000
 Hepatic insufficiency4 (2.9)1 (2.5)1.000
 Renal insufficiency27 (19.9)12 (30.0)0.174
 Cerebrovascular event3 (2.2)2 (5.0)0.694
 Myocardial infarction9 (6.6)2 (5.0)1.000
 tamponade21 (15.4)9 (22.5)0.297
 Marfan Syndrome6 (4.4)3 (7.5)0.711
 Smoking32 (23.5)8 (20.0)0.640
Laboratory test
 Leucocyte (109/L)12.0 ± 4.013.0 ± 3.40.147
 Hemoglobin (g/L)132.0 (123.0, 143.0)137.5 (124.8, 150.3)0.112
 Platelet (109/L)147.0 (121.3, 201.8)161.5 (140.5, 200.0)0.317
 ALT (U/L)26.5 (19.3, 38.0)30.5 (19.0, 41.4)0.930
 Creatinine (μmol/L)85.0 (68.0, 107.8)89.5 (70.3, 132.0)0.437
 Troponin I (ng/ml)0.02 (0.01, 0.05)0.02 (0.01, 0.09)0.782
 PaO2 (mmHg)85.5(71.2, 101.7)80.0(67.7, 109.2)0.897
Surgical procedure
 Total arch replacement129 (94.9)38 (95.0)1.000
 Hemi arch replacement7 (5.1)2 (5.0)1.000
 Concomitant CABG10 (7.4)2 (5.0)1.000
CPB
 CPB time (min)167.5 (143.5, 186.8)162.5 (147.0, 191.5)0.806
 ACC time (min)97.5 (84.0, 109.8)96.0 (87.3, 117.3)0.604
 DHCA time (min)28.0 (22.0, 31.8)24.0 (19.0, 28.0)0.041*
 Minimum temperature in CPB (°C)22.3 (22.1, 24.4)22.1 (21.5, 23.5)0.040*
 PaO2/FiO2 ratio meet hypoxemia criteria112.9 (94.3, 155.0)95.0 (82.9, 127.1)0.076
  1. AADA Acute type A aortic dissection, PSM Propensity score-matching, iNO Inhaled nitric oxide, BMI Body mass index, COPD Chronic obstructive pulmonary disease, ALT Alanine transaminase, CABG Coronary artery bypass graft, CPB Cardiopulmonary bypass, ACC Aortic cross-clamp, DHCA Deep hypothermic circulatory arrest, PaO2 Partial pressure of oxygen, FiO2 Fraction of inspired oxygen
  2. *p < 0.05
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