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Table 2 Baseline characteristics of patients with AADA and hypoxemia at 24 h after surgery: post-PSM

From: Effects of inhaled nitric oxide for postoperative hypoxemia in acute type A aortic dissection: a retrospective observational study

Patients’ CharacteristicsControl (N = 94)iNO treatment (N = 40)p-value
Age, y50.5 ± 11.249.9 ± 11.20.763
Men75 (79.8)31 (77.5)0.766
BMI26.1(24.9, 28.6)26.5(24.5, 27.7)0.719
Comorbidity
 Hypertension65 (69.1)32 (80.0)0.199
 Diabetes1 (1.1)2 (5.0)0.159
 COPD2 (2.1)1 (2.5)0.894
 Hepatic insufficiency1 (1.1)1 (2.5)0.530
 Renal insufficiency20 (21.3)12 (30.0)0.163
 Cerebrovascular event2 (2.1)2 (5.0)0.734
 Tamponade17 (18.1)9 (22.5)0.554
 Myocardial infarction8 (8.5)2 (5.0)0.479
 Marfan Syndrome3 (3.2)3 (7.5)0.270
 Smoking23 (24.5)8 (20)0.575
Laboratory test
 Leucocyte (109/L)11.8 ± 3.813.0 ± 3.30.086
 Hemoglobin (g/L)134.0(124.0, 143.0)137.5(124.8, 150.3)0.652
 Platelet (109/L)162.0 (127.0, 212.0)161.5(140.5, 200.0)0.726
 ALT (U/L)27.0(20.0, 39.5)30.5(19.0, 41.4)0.934
 Creatinine (μmol/L)82.0(66.5, 108.2)89.5(70.2, 132.0)0.256
 Troponin I (ng/ml)0.02(0.01, 0.07)0.02(0.01, 0.08)0.489
 PaO2 (mmHg)83.5(70, 99)80(67.7, 109.2)0.132
 Surgical procedure
 Total arch replacement89 (94.7)38 (95.0)1.000
 Hemi arch replacement5 (5.3)2 (5.0)1.000
 Concomitant CABG9 (9.6)2 (5.0)0.377
CPB
 CPB time (min)167.5(149.0, 183.0)162.5(147.0, 191.5)0.808
 ACC time (min)97.5(84.0, 109.3)96.0(87.3, 117.3)0.569
 DHCA time (min)26.0(20.8, 30.0)24.0 (19.0, 28.0)0.143
 Minimum temperature in CPB (°C)22.1(22.1, 24.3)22.1(21.5, 23.5)0.129
 PaO2/FiO2 ratio meet hypoxemia criteria109.0(85.2, 130.1)95.0(82.9, 127.1)0.524
  1. AADA Acute type A aortic dissection, PSM Propensity score-matching, iNO Inhaled nitric oxide, BMI Body mass index, COPD Chronic obstructive pulmonary disease, ALT Alanine transaminase, CPB Cardiopulmonary bypass, ACC Aortic cross-clamp, DHCA Deep hypothermic circulatory arrest, PaO2 Partial pressure of oxygen, FiO2 Fraction of inspired oxygen
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