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Table 2 Baseline characteristics of patients with AADA and hypoxemia at 24 h after surgery: post-PSM

From: Effects of inhaled nitric oxide for postoperative hypoxemia in acute type A aortic dissection: a retrospective observational study

Patients’ Characteristics

Control (N = 94)

iNO treatment (N = 40)

p-value

Age, y

50.5 ± 11.2

49.9 ± 11.2

0.763

Men

75 (79.8)

31 (77.5)

0.766

BMI

26.1(24.9, 28.6)

26.5(24.5, 27.7)

0.719

Comorbidity

 Hypertension

65 (69.1)

32 (80.0)

0.199

 Diabetes

1 (1.1)

2 (5.0)

0.159

 COPD

2 (2.1)

1 (2.5)

0.894

 Hepatic insufficiency

1 (1.1)

1 (2.5)

0.530

 Renal insufficiency

20 (21.3)

12 (30.0)

0.163

 Cerebrovascular event

2 (2.1)

2 (5.0)

0.734

 Tamponade

17 (18.1)

9 (22.5)

0.554

 Myocardial infarction

8 (8.5)

2 (5.0)

0.479

 Marfan Syndrome

3 (3.2)

3 (7.5)

0.270

 Smoking

23 (24.5)

8 (20)

0.575

Laboratory test

 Leucocyte (109/L)

11.8 ± 3.8

13.0 ± 3.3

0.086

 Hemoglobin (g/L)

134.0(124.0, 143.0)

137.5(124.8, 150.3)

0.652

 Platelet (109/L)

162.0 (127.0, 212.0)

161.5(140.5, 200.0)

0.726

 ALT (U/L)

27.0(20.0, 39.5)

30.5(19.0, 41.4)

0.934

 Creatinine (μmol/L)

82.0(66.5, 108.2)

89.5(70.2, 132.0)

0.256

 Troponin I (ng/ml)

0.02(0.01, 0.07)

0.02(0.01, 0.08)

0.489

 PaO2 (mmHg)

83.5(70, 99)

80(67.7, 109.2)

0.132

 Surgical procedure

 Total arch replacement

89 (94.7)

38 (95.0)

1.000

 Hemi arch replacement

5 (5.3)

2 (5.0)

1.000

 Concomitant CABG

9 (9.6)

2 (5.0)

0.377

CPB

 CPB time (min)

167.5(149.0, 183.0)

162.5(147.0, 191.5)

0.808

 ACC time (min)

97.5(84.0, 109.3)

96.0(87.3, 117.3)

0.569

 DHCA time (min)

26.0(20.8, 30.0)

24.0 (19.0, 28.0)

0.143

 Minimum temperature in CPB (°C)

22.1(22.1, 24.3)

22.1(21.5, 23.5)

0.129

 PaO2/FiO2 ratio meet hypoxemia criteria

109.0(85.2, 130.1)

95.0(82.9, 127.1)

0.524

  1. AADA Acute type A aortic dissection, PSM Propensity score-matching, iNO Inhaled nitric oxide, BMI Body mass index, COPD Chronic obstructive pulmonary disease, ALT Alanine transaminase, CPB Cardiopulmonary bypass, ACC Aortic cross-clamp, DHCA Deep hypothermic circulatory arrest, PaO2 Partial pressure of oxygen, FiO2 Fraction of inspired oxygen