Table 3 Endpoints
Variable | the UFH group (n = 109) | the UFH-LMWH group (n = 99) | P value | the LMWH group (n = 97) | P value |
|---|---|---|---|---|---|
Patients | Patients | Patients | |||
Primary endpoints | |||||
All thromboembolic events | 2 (1.8%) | 0 (0) | – | 0 (0) | – |
thromboembolic events a | 1 (0.9%) | 0 (0) | – | 0 (0) | – |
All bleeding events | 3 (2.8%) | 5 (5.1%) | 0.39 | 10 (10.3%) | 0.03 |
bleeding events b | 2 (1.8%) | 3 (3.0%) | 0.91 | 5 (5.2%) | 0.35 |
Secondary endpoints | |||||
Volume of drainage (ml) | |||||
postoperative day 1 | 296.8 ± 186.2 | 291.2 ± 170.3 | 1.00 | 263.8 ± 175.3 | 0.55 |
postoperative day 2 | 203.5 ± 103.7 | 188.2 ± 113.2 | 0.95 | 187.5 ± 111.6 | 0.89 |
postoperative day 3 | 80.8 ± 66.9 | 91.5 ± 73.2 | 0.80 | 86.5 ± 68.4 | 1.00 |
postoperative day 4 | 40.0 ± 40.3 | 47.8 ± 49.6 | 0.68 | 40.8 ± 49.4 | 1.00 |
ICU length of stay (d) | 4.2 ± 2.5 | 4.0 ± 1.4 | 0.97 | 3.7 ± 0.8 | 0.08 |
Postoperative length of stay (d) | 15.8 ± 4.2 | 15.3 ± 3.5 | 0.98 | 14.6 ± 4.1 | 0.08 |
Time of achieving target INR (d) | 10.9 ± 2.8 | 10.5 ± 3.2 | 0.78 | 10.0 ± 2.2 | 0.06 |
Third endpoints | |||||
Hospital costs (yuan) | 108,884.5 ± 26,641.7 | 109,900.5 ± 37,380.7 | 1.00 | 105,976.4 ± 22,249.5 | 1.00 |
Medicine costs (yuan) | 41,214.3 ± 14,809.6 | 41,405.9 ± 13,368.3 | 1.00 | 39,176.9 ± 10,788.4 | 0.81 |
Medicine costs /Hospital costs | 0.37 ± 0.07 | 0.38 ± 0.07 | 1.00 | 0.37 ± 0.07 | 1.00 |