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Table 3 Clinical characteristics of patients with NLSLNM and LSLNM

From: Is lobe specific lymph node dissection adequate for cN0–1 non-small cell lung cancer?

VariablesNLSLNM (n = 129)LSLNM (n = 230)P value
Sex  0.149
 Male61 (47.3%)127 (55.2%) 
 Female68 (52.7%)103 (44.8%) 
Age, years  0.176
 Median (range)61 (26–83)60.5 (27–80) 
 Smoking history42 (32.6%)115 (50.0%)0.001
 Hypertension21 (16.3%)66 (28.7%)0.008
 Diabetes8 (6.2%)14 (6.1%)0.965
 Other pulmonary diseases5 (3.9%)5 (2.2%)0.544
 Other malignant tumors within 5 years0 (0)4 (1.7%)0.326
CEA level  0.004
 >5 ng/ml65 (50.4%)80 (34.8%) 
 ≤5 ng/ml64 (49.6%)150 (65.2%) 
Tumor location  < 0.001
 RUL19 (14.7%)59 (25.7%) 
 RLL54 (41.9%)46 (20.0%) 
 LUL26 (20.2%)71 (30.9%) 
 LLL30 (23.3%)54 (23.5%) 
CT characteristics  0.404
 GGO1 (0.8%)1 (0.4%) 
 Partially solid4 (3.1%)14 (6.1%) 
 Solid124 (96.1%)215 (93.5%) 
Clinical T stage  0.493
 T1a2 (1.6%)4 (1.7%) 
 T1b19 (14.7%)49 (21.3%) 
 T1c47 (36.4%)70 (30.4%) 
 T2a27 (20.9%)56 (24.3%) 
 T2b20 (15.5%)27 (11.7%) 
 T313 (10.1%)19 (8.3%) 
 T41 (0.8%)5 (2.2%) 
Clinical N stage  0.647
 N0118 (91.5%)207 (90.0%) 
 N111 (8.5%)23 (10.0%) 
Surgical approach  0.052
 Thoracotomy71 (55.0%)102 (44.3%) 
 VATS58 (45.0%)128 (55.7%) 
Surgical resection  0.345
 Segmentectomy2 (1.6%)6 (2.6%) 
 Lobectomy120 (93.0%)207 (90.0%) 
 Sleeve lobectomy2 (1.6%)11 (4.8%) 
 Pneumonectomy5 (3.9%)6 (2.6%) 
  1. NLSLNM non-lobe specific lymph node metastasis; LSLNM lobe specific lymph node metastasis; CEA carcinoembryonic antigen; RUL right upper lobe; RLL right lower lobe; LUL left upper lobe; LLL left lower lobe; GGO ground-glass opacity; VATS video assisted thoracic surgery
  2. Values are N (percentage) unless otherwise specified