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Table 4 Pathological characteristics of patients with NLSLNM and LSLNM

From: Is lobe specific lymph node dissection adequate for cN0–1 non-small cell lung cancer?

Variables

NLSLNM (n = 129)

LSLNM (n = 230)

P value

Anatomical type

  

0.168

 Central

31 (24.0%)

71 (30.9%)

 

 Peripheral

98 (76.0%)

159 (69.1%)

 

Histology

  

0.022

 Adenocarcinoma

103 (79.8%)

161 (70.0%)

 

 SCC

14 (10.9%)

52 (22.6%)

 

 Others

12 (9.3%)

17 (7.4%)

 

Cell differentiation

  

0.480

 Well-moderate

3 (2.3%)

2 (0.9%)

 

 Moderate

25 (19.4%)

56 (24.3%)

 

 Moderate-poor

62 (48.1%)

111 (48.3%)

 

 Poor

33 (25.6%)

52 (22.6%)

 

 NAa

6 (4.7%)

9 (3.9%)

 

Pathological T stage

  

0.886

 T1a

1 (0.8%)

2 (0.9%)

 

 T1b

17 (13.2%)

31 (13.5%)

 

 T1c

24 (18.6%)

33 (14.5%)

 

 T2a

54 (41.9%)

112 (48.7%)

 

 T2b

17 (13.2%)

24 (10.4%)

 

 T3

12 (9.3%)

21 (9.1%)

 

 T4

4 (3.1%)

7 (3.0%)

 

Pathological TNM stage

  

0.853

 IIIA

113 (87.6%)

203 (88.3%)

 

 IIIB

16 (12.4%)

27 (11.7%)

 

Tumor sizeb, cm

  

0.830

 Median (range)

3.0 (0.8–8.0)

3.0 (0.9–10.0)

 

 Visceral pleural invasion

51 (39.5%)

73 (31.7%)

0.136

 Lymphovascular invasion

30 (23.3%)

44 (19.1%)

0.354

 Skip N2 metastasis

25 (19.4%)

65 (28.3%)

0.062

N1 involvement

 10

51 (39.5%)

61 (26.5%)

0.011

 11

47 (36.4%)

48 (20.9%)

0.001

 12

83 (64.3%)

124 (53.9%)

0.055

  1. NLSLNM non-lobe specific lymph node metastasis; LSLNM lobe specific lymph node metastasis; SCC Squamous cell carcinoma; NA not available
  2. a Cases that were not available, and were hence excluded when calculating the p-value
  3. b Tumor size was defined as the maximum diameter of the pathological specimens
  4. Values are N (percentage) unless otherwise specified