From: Is lobe specific lymph node dissection adequate for cN0–1 non-small cell lung cancer?
Variables | NLSLNM (n = 129) | LSLNM (n = 230) | P value |
---|---|---|---|
Anatomical type | 0.168 | ||
Central | 31 (24.0%) | 71 (30.9%) | |
Peripheral | 98 (76.0%) | 159 (69.1%) | |
Histology | 0.022 | ||
Adenocarcinoma | 103 (79.8%) | 161 (70.0%) | |
SCC | 14 (10.9%) | 52 (22.6%) | |
Others | 12 (9.3%) | 17 (7.4%) | |
Cell differentiation | 0.480 | ||
Well-moderate | 3 (2.3%) | 2 (0.9%) | |
Moderate | 25 (19.4%) | 56 (24.3%) | |
Moderate-poor | 62 (48.1%) | 111 (48.3%) | |
Poor | 33 (25.6%) | 52 (22.6%) | |
NAa | 6 (4.7%) | 9 (3.9%) | |
Pathological T stage | 0.886 | ||
T1a | 1 (0.8%) | 2 (0.9%) | |
T1b | 17 (13.2%) | 31 (13.5%) | |
T1c | 24 (18.6%) | 33 (14.5%) | |
T2a | 54 (41.9%) | 112 (48.7%) | |
T2b | 17 (13.2%) | 24 (10.4%) | |
T3 | 12 (9.3%) | 21 (9.1%) | |
T4 | 4 (3.1%) | 7 (3.0%) | |
Pathological TNM stage | 0.853 | ||
IIIA | 113 (87.6%) | 203 (88.3%) | |
IIIB | 16 (12.4%) | 27 (11.7%) | |
Tumor sizeb, cm | 0.830 | ||
Median (range) | 3.0 (0.8–8.0) | 3.0 (0.9–10.0) | |
Visceral pleural invasion | 51 (39.5%) | 73 (31.7%) | 0.136 |
Lymphovascular invasion | 30 (23.3%) | 44 (19.1%) | 0.354 |
Skip N2 metastasis | 25 (19.4%) | 65 (28.3%) | 0.062 |
N1 involvement | |||
10 | 51 (39.5%) | 61 (26.5%) | 0.011 |
11 | 47 (36.4%) | 48 (20.9%) | 0.001 |
12 | 83 (64.3%) | 124 (53.9%) | 0.055 |