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Table 1 Kidney Disease Improving Global Outcomes (KDIGO): primary outcome defined by this criterion for acute kidney injury

From: Is there a renoprotective value to leukodepletion during heart valve surgery? A randomized controlled trial (ROLO)

Stage Serum creatinine (SCr) criteria Urine output criteria
1 Increase ≥26 μmol/L within 48 h or
increase ≥1.5 to 1.9 x reference baseline SCr
< 0.5 mL/kg/hr. for > 6 consecutive hrs
2 Increase ≥2 to 2.9 x reference baseline SCr < 0.5 mL/kg/hr. for > 12 h
3 Increase ≥3 x reference baseline SCr or
increase ≥354 μmol/L or
commenced on renal replacement therapy irrespective of stage
< 0.3 mL/kg/hr. for > 24 h or anuria for 12 h