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Table 1 Summary of included studies

From: Midterm outcomes of early versus late surgery for infective endocarditis with neurologic complications: a meta-analysis

Author Year Follow-up (months) Definition of early surgery Mean or median time to surgery (day) Patients (n) Early (n) Late (n)
Early Early Late
Thuny [13] 2009 6 < 7 days 3 19 241 95 146
Kim [14] 2011 62 < 14 days 3 20 56 34 22
Barsic [15] 2012 12 < 7 days NA NA 56 34 22
Oh [16] 2016 51 < 7 days 4 17 39 20 19
Samura [17] 2019 60 <  3 days 1 16 90 45 45
Age, median or mean ± SD Female (%) Diabetes (%) CHF (%)
Early Late Early Late Early Late Early Late
53 ± 16 58 ± 15 27 21 10 15 46 40
44 ± 14 40 ± 16 32 36 9 14 NA NA
53 57 31 32 24 17 NA NA
53 ± 15 45 ± 15 25 42 10 5 50 42
64 65 44 36 24 36 NA NA
Valve involved Prosthetic valve (%) Cerebral hemorrhage (%)
Early Late Early Late Early Late
A-64%, M-53%, B-19% M-70%, B-50%, T-22% 21 31 2 5
A-35%, M-53%, B-12% A-27%, M-55%, B-18% 3 27 14 41
A-60%, M-43% A-48%, M-58% 22 23 NA NA
A-55%, M-55%, T-5% A-47%, M-79% 45 37 20 32
A-45%, M-71% A-45%, M-64% 19 21 0 0
  1. A Aortic valve, B Aortic and mitral valves, CHF Congestive heart failure, M Mitral valve, NA Not available, T Tricuspid valve