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Table 1 Summary of included studies

From: Midterm outcomes of early versus late surgery for infective endocarditis with neurologic complications: a meta-analysis

Author

Year

Follow-up (months)

Definition of early surgery

Mean or median time to surgery (day)

Patients (n)

Early (n)

Late (n)

Early

Early

Late

Thuny [13]

2009

6

< 7 days

3

19

241

95

146

Kim [14]

2011

62

< 14 days

3

20

56

34

22

Barsic [15]

2012

12

< 7 days

NA

NA

56

34

22

Oh [16]

2016

51

< 7 days

4

17

39

20

19

Samura [17]

2019

60

<  3 days

1

16

90

45

45

Age, median or mean ± SD

Female (%)

Diabetes (%)

CHF (%)

Early

Late

Early

Late

Early

Late

Early

Late

53 ± 16

58 ± 15

27

21

10

15

46

40

44 ± 14

40 ± 16

32

36

9

14

NA

NA

53

57

31

32

24

17

NA

NA

53 ± 15

45 ± 15

25

42

10

5

50

42

64

65

44

36

24

36

NA

NA

Valve involved

Prosthetic valve (%)

Cerebral hemorrhage (%)

Early

Late

Early

Late

Early

Late

A-64%, M-53%, B-19%

M-70%, B-50%, T-22%

21

31

2

5

A-35%, M-53%, B-12%

A-27%, M-55%, B-18%

3

27

14

41

A-60%, M-43%

A-48%, M-58%

22

23

NA

NA

A-55%, M-55%, T-5%

A-47%, M-79%

45

37

20

32

A-45%, M-71%

A-45%, M-64%

19

21

0

0

  1. A Aortic valve, B Aortic and mitral valves, CHF Congestive heart failure, M Mitral valve, NA Not available, T Tricuspid valve