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Fig. 2 | Journal of Cardiothoracic Surgery

Fig. 2

From: Mechanical stretching of the pulmonary vein mediates pulmonary hypertension due to left heart disease by regulating SAC/MAPK pathway and the expression of IL-6 and TNF-α

Fig. 2

a Establishment of the PH-LHD model. The metal titanium clip (yellow arrow) was located at the ascending aorta of rats in the PH-LHD group by Doppler echocardiography. The PH-LHD model was established, and the position of the titanium clip was shown in the ascending aorta above the coronary artery. b RVP and LAP were determined in PH-LHD model rats. Representative images of RVP and LAP in sham and PH-LHD model rats are shown (P < 0.05). c Doppler echocardiography of left cardiac function in PH-LHD model rats. Representative images of left ventricular dysfunction in rats were assessed by Doppler echocardiography. a Sham model b PH-LHD model

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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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