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Table 1 Complication rates of talc insufflation for MPEs

From: Complications of thoracoscopic talc insufflation for the treatment of malignant pleural effusions: a meta-analysis

Complication Number of studies Number of cases Total patients Incidence [95% CI] p-value
Pain 8 165 1378 20 [8, 37] < 0.001
Fever 11 190 1574 14 [7, 23] < 0.001
Pneumothorax 3 29 461 6 [1, 14] < 0.001
Pneumonia 6 52 1058 4 [0, 12] 0.02
Emphysema 6 54 1577 3 [1, 7] < 0.001
Prolonged air leakage 5 57 1661 3 [0, 7] 0.01
Prolonged drainage 2 26 823 3 [2, 4] < 0.001
Thromboembolism 2 17 496 3 [2, 5] < 0.001
Nausea/vomiting 3 5 234 2 [0, 5] 0.04
Respiratory insufficiency 3 5 178 2 [0, 5] 0.02
Hypotension 2 5 188 2 [0, 5] 0.01
Lung injury 3 11 704 2 [1, 3] < 0.001
Pulmonary embolism 4 14 828 2 [0, 4] 0.02
Arrythmia 6 20 828 2 [0, 4] < 0.001
Empyema 11 28 1883 1 [0, 2] < 0.001
Wound infection 5 15 1240 1 [0, 2] < 0.001
Renal dysfunction 2 6 401 1 [0, 3] < 0.001
Re-expansion pulmonary edema 5 18 1188 1 [0, 3] 0.01
Respiratory failure 7 13 1863 0 [0, 1] 0.24
Acute respiratory distress syndrome 14 27 2889 0 [0, 1] 0.36
Bleeding 7 13 2148 0 [0, 1] < 0.001
Tumor recurrence at port 2 4 428 0 [0, 1] 0.17
Myocardial infarction 3 5 1253 0 [0, 1] < 0.001
Pulmonary edema 3 3 561 0 [0, 2] 0.44