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Table 1 Patient’s characteristics (pre-LVAD)

From: Impact of tricuspid regurgitation on late right ventricular failure in left ventricular assist device patients ~can prophylactic tricuspid annuloplasty prevent late right ventricular failure? ~

 

Overall

TR ≥ moderate (n = 41)

TR ≤ mild (n = 106)

p value

Age

41.9 ± 14.3

43.7 ± 13.2

41.2 ± 14.7

0.33

Male

101 (69%)

30 (73%)

71 (67%)

0.55

Etiology

 DCM, n(%)

89 (61%)

26 (63%)

63 (59%)

0.71

 dHCM, n(%)

22 (15%)

5 (12%)

17 (16%)

0.80

 ICM, n(%)

15 (10%)

2 (5%)

13 (12%)

0.24

 Others, n(%)

21 (14%)

8 (20%)

13 (12%)

0.30

Etiology of TR

 pulmonary hypertension

84 (58%)

29 (71%)

55 (52%)

0.04*

 severe annular dilation

54 (37%)

29 (71%)

25 (24%)

< 0.0001*

 induced by pacing lead

4 (3%)

2 (5%)

2 (2%)

0.31

INTERMACS profile

 profile 1, n(%)

33 (22%)

11 (27%)

22 (21%)

0.51

 profile 2, n(%)

51 (35%)

17 (41%)

34 (32%)

0.34

 profile 3, n(%)

58 (39%)

10 (24%)

48 (45%)

0.02*

 profile 4, n(%)

5 (3%)

3 (7%)

2 (2%)

0.13

IABP, n(%)

32 (22%)

15 (37%)

17 (16%)

0.01*

ECMO, n(%)

11 (7%)

4 (10%)

7 (7%)

0.50

ventilation, n(%)

25 (17%)

10 (24%)

15 (14%)

0.15

pacing device, n(%)

80 (54%)

20 (49%)

60 (57%)

0.46

LVDd (mm)

69.6 ± 12.7

68.1 ± 12.0

70.3 ± 12.9

0.35

LVDs (mm)

64.1 ± 13.6

62.4 ± 13.0

64.8 ± 13.9

0.35

LVEF(%)

20.7 ± 8.6

20.7 ± 9.7

20.7 ± 8.2

0.99

RVDd (mm)

40.0 ± 9.9

45.8 ± 9.8

37.8 ± 9.1

0.0002*

TAPSE (mm/s)

14.3 ± 4.7

14.4 ± 3.9

14.2 ± 4.9

0.89

TRPG (mmHg)

31.4 ± 14.0

38.0 ± 17.3

29.0 ± 11.7

0.0012*

PAP systolic (mmHg)

40.0 ± 13.5

45.3 ± 14.2

37.9 ± 12.8

0.0041*

PAP diastolic (mmHg)

19.7 ± 7.9

22.3 ± 7.8

18.7 ± 7.8

0.02*

PAP mean (mmHg)

27.8 ± 9.8

31.6 ± 9.8

26.3 ± 9.4

0.0045*

PCWP (mmHg)

20.0 ± 8.5

22.6 ± 8.6

19.0 ± 8.3

0.03*

RAP (mmHg)

7.8 ± 4.9

9.2 ± 4.6

7.3 ± 4.9

0.04*

CI(L/min/m2)

2.25 ± 0.77

2.23 ± 0.97

2.26 ± 0.69

0.80

RAP/PCWP

0.40 ± 0.29

0.42 ± 0.24

0.40 ± 0.31

0.65

PAPi

3.80 ± 3.20

3.26 ± 2.80

4.01 ± 3.33

0.23

RVSWI (mmHg×ml/m2)

537 ± 279

567 ± 359

525 ± 242

0.44

BUN (mg/dl)

20.2 ± 12.4

24.4 ± 17.5

18.5 ± 9.3

0.0094*

Cr (mg/dl)

1.06 ± 0.49

1.24 ± 0.67

0.99 ± 0.38

0.0054*

Ccr (ml/min/m2)

71.2 ± 34.5

63.8 ± 34.1

73.9 ± 34.4

0.12

T-Bil (mg/dl)

1.06 ± 0.75

1.25 ± 0.72

0.99 ± 0.75

0.07

BNP (pg/μl)

412 (30.8–4206)

591 (44–3022)

341 (30.8–4206)

0.0006*

  1. BNP brain natriuretic peptide, BUN blood urea nitrogen, Ccr creatinine clearance, CI cardiac index, Cr serum creatinine, DCM dilated cardiomyopathy, dHCM dilated phase hypertrophic cardiomyopathy, ECMO extracorporeal membrane oxygenation, IABP intra-aortic balloon pumping, ICM ischemic cardiomyopathy, INTERMACS Interagency Registry for Mechanically Assisted Circulatory Support, LVAD left ventricular assist device, LVDd left ventricular end-diastolic dimension, LVDs left ventricular end-systolic dimension, LVEF left ventricular ejection fraction, PAP pulmonary artery pressure, PAPi pulmonary artery pulsatility index, PCWP pulmonary capillary wedge pressure, RAP right atrial pressure, RVDd right ventricular end diastolic dimension, RVSWI right ventricular stroke work index, TAPSE tricuspid annular plane systolic excursion, T-Bil total bilirubin, TR tricuspid regurgitation, TRPG tricusid regurgitation peak gradient