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Table 2 Clinical characteristics of our elective cardiac surgical patients with and without anemia

From: Preoperative anemia and transfusion in cardiac surgery: a single-centre retrospective study

Parameters Non-Anemic (N = 678) Anemic (N = 119) Total (N = 797) P value* Mild Anemic (N = 80) Mod/Sev. Anemic (N = 39) P value†
Demographics
 Age (yr) 66 (56–73) 69 (63–76) 66 (56–73) 0.003 70 (64–76) 66 (57–73) 0.068
 Female 206 (30) 56 (47) 262 (33) 0.001 33 (41) 23 (59) 0.081
 Weight 85 (73–97) 79 (68–90) 83 (71–96) 0.002 82 (72–93) 73 (63–84) 0.005
 BMI (kg/m2) 29 (25–33) 29 (25–33) 29 (25–33) 0.340 29 (25–34) 28 (23–31) 0.031
 BSA (m2) 2.0 (1.8–2.2) 1.9 (1.7–2.1) 2.0 (1.8–2.1) < 0.001 1.9 (1.8–2.1) 1.8 (1.6–1.9) 0.006
Surgical procedures    0.175     NA
 Isolated CABG 157 (23) 34 (29) 191 (24)   24 (30) 10 (26)  
 Isolated valve 290 (43) 55 (46) 345 (43)   35 (44) 20 (51)  
 CABG & valve 61 (9) 13 (11) 74 (9)   7 (9) 6 (15)  
 Aortic surgery 96 (14) 11 (9) 107 (13)   9 (11) 2 (5)  
 Adult congenital 48 (7) 5 (4) 53 (7)   4 (5) 1 (3)  
 Others 26 (4) 1 (1) 27 (3)   1 (1) 0 (0)  
Surgical parameters
 Repeat sternotomy 74 (11) 15 (13) 89 (11) 0.635 13 (16) 2 (5) 0.139
 Cross-clamp time (min) 84 (61–110) 77 (59–103) 83 (61–110) 0.252 80 (58–106) 76 (59–102) 0.777
 Total bypass time (min) 106 (80–141) 99 (81–136) 104 (80–141) 0.455 102 (80–144) 95 (84–127) 0.551
 DHCA 32 (5) 6 (5) 38 (5) 0.817 6 (8) 0 (0) 0.176
Co-morbidities
 Diabetes 161 (24) 58 (49) 219 (27) < 0.0001 38 (48) 20 (51) 0.845
 CVA 41 (6) 14 (12) 55 (7) 0.030 6 (8) 8 (21) 0.065
Lab and imaging parameters
 eGFR (ml/min/1.73 m2) 80 (66–92) 60 (41–85) 78 (63–92) < 0.0001 67 (45–85) 56 (18–83) 0.046
 LVEF (%)     0.029    0.004
  ≥ 50 560 (83) 92 (77) 652 (82)   66 (83) 26 (67)  
 < 50 95 (14) 27 (23) 122 (15)   14 (18) 13 (33)  
Preoperative intervention
 Referral to BCC NA 9 (8) NA NA 5 (6) 4 (10) 0.473
 Received treatment at BCC NA 3 (3) NA NA 0 (0) 3 (8) 0.033
 Days from PAC to surgery 7 (2–15) 7 (2–17) 7 (2–15) 0.990 7 (1–14) 7 (2–18) 0.537
  1. BCC blood conservation clinic, BMI body mass index, BSA body surface area, CABG coronary artery bypass graft, CVA cerebrovascular accident, DHCA deep hypothermic circulatory arrest, eGFR estimated glomerular filtration rate, Hb hemoglobin, LVEF left ventricular ejection fraction, min minute, mod/sev moderate/severe, PAC pre-admission clinic, P value * p value between anemic and non-anemic groups, P value† p value between mild anemic and moderate/severe anemic groups, yr year