Survival risk prediction model for patients with pT1–3 N0M0 esophageal squamous cell carcinoma after R0 esophagectomy with two-field lymphadenectomy for therapeutic purposes

Table 2 Factors associated with OS or DFS according to univariate analysis for pT_1 − 3N₀M₀ ESCC patients after surgery alone

Factors	Number	OS		p	DFS		p
Factors	Number	3-year	5-year	p	3-year	5-year	p
Gender
Male	303	71.3	59.7	0.162	62.4	53.1	0.366
Female	185	75.7	65.9		65.9	53.0
Age
≤ 65 years	339	74.0	65.2	0.019	66.1	56.0	0.064
> 65 years	149	70.5	55.0		54.8	46.3
Site of lesion
Upper	61	57.4	47.5	0.033	44.3	36.1	0.008
Middle	344	74.1	62.5		64.2	53.2
Lower	83	79.5	71.1		75.9	65.1
Length of lesion
< 5 cm	259	72.6	61.8	0.907	63.3	51.7	0.558
≥ 5 cm	229	73.4	62.4		64.2	54.6
SLNs in CT
No	373	76.4	66.0	0.002	67.6	56.8	0.001
Yes	115	61.7	49.6		51.3	40.9
Dissected LNs
< 12	337	68.8	58.5	0.034	58.8	51.0	0.149
≥ 12	151	82.1	70.2		74.8	57.6
Differentiation
Well/moderate	450	73.3	62.2	0.163	64.2	53.3	0.323
Poor	38	68.3	55.3		57.9	50.0
pT
pT₁	102	89.2	84.3	< 0.00	82.4	71.6	< 0.001
pT₂	126	77.0	65.1		65.1	50.8
pT₃	260	64.6	51.9		55.8	46.9

Abbreviations and definitions: OS overall survival, DFS disease-free survival, ESCC esophageal squamous cell carcinoma, dissected LNs the number of dissected lymph nodes at the time of surgery, SLNs in CT small lymph nodes in mediastinum (diameter < 1 cm) in CT image prior to surgery

ISSN: 1749-8090