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Table 1 Baseline preoperative characteristics of patients who underwent valve surgery via the use of CORKNOT®

From: Incidence of valvular regurgitation and leaflet perforation by using automated titanium fasteners (CORKNOT®) in heart valve repair or replacement: less usual than reported

Demographics Subclass distribution Comparison group
Variables Valve Replacement
(n = 89)
Combined Repair and replacement
(n = 10)
Valve
Repair
(n = 33)
Single Mitral Valve Repair
(n = 29)
Double Valve Repair
(n = 4)
Single Mitral Valve Replacement
(n = 37)
Single Aortic Valve Replacement
(n = 43)
p-value
Age – year (mean ± SD) 61.2 ± 12.0 66.6 ± 10.9 55.1 ± 12.2 54.6 ± 12.6 58.8 ± 9.5 60.5 ± 10.3 62.9 ± 12.5 0.357
Gender        19/37  34/43 0.009
 Male 59 (66.3%) 6 (60%) 26 (78.8%) 23 (79.3%) 3 (75%) 19 (51.4%) 34 (79.1%)  
 Female 30 (33.7%) 4 (40%) 7 (21.2%) 6 (20.7%) 1 (25%) 18 (48.6%) 9 (20.9%)
Ethnicity        26/37  32/43 0.031
 Chinese 65 (73.0%) 8 (80%) 22 (66.7%) 19 (65.5%) 3 (75%) 26 (70.3%) 32 (74.4%)  
 Malay 5 (5.6%) 0 3 (9.1%) 3 (10.3%) 0 4 (5.0%) 4 (9.3%)
 Indian 5 (5.6%) 0 4 (12.1%) 4 (13.8%) 0 5 (6.3%) 1 (2.3%)
 Caucasian 3 (3.4%) 0 0 3 (3.8%) 3 (7.0%)
 Others 11 (12.4%) 2 (20%) 4 (12.1%) 3 (10.3%) 1 (25%) 7 (18.9%) 3 (7.0%)
Body Surface Area – m2 (mean ± SD) 1.81 ± 0.19 1.8 ± 0.2 1.73 ± 0.25 1.82 ± 0.21 0.129
Pre-operative Ejection Fraction – % (mean ± SD) 55.0 ± 12.0 59.0 ± 5.2 56.2 ± 14.4 57.8 ± 13.0 45.0 ± 21.2 59.5 ± 9.8 52.0 ± 13.5 0.007
Co-morbidities
 Stroke 5 (5.6%) 0 0 0 0 2 (5.4%) 2 (4.7%) 1.00
 Transient Ischemic Attack 1 (1.1%) 0 0 0 0 0 1 (2.3%) 1.00
 Congestive Cardiac Failure 16 (18.0%) 1 (10%) 3 (9.1%) 2 (6.9%) 1 (25%) 8 (21.6%) 5 (11.6%) 0.244
 Hypertension 45 (50.6%) 5 (50%) 16 (48.5%) 14 (48.3%) 2 (50%) 14 (37.8%) 25 (58.1%) 0.078
 Hyperlipidemia 47 (52.8%) 3 (30%) 14 (42.4%) 12 (41.4%) 2 (50%) 16 (43.2%) 30 (69.8%) 0.023
 Peripheral Arterial Disease 7 (7.9%) 0 0 0 0 3 (8.1%) 3 (7.0%) 1.00
 Myocardial Infarction 9 (10.1%) 1 (10%) 2 (6.1%) 2 (6.9%) 0 3 (8.1%) 6 (14.0%) 0.494
 Diabetes 23 (25.8%) 1 (10%) 6 (18.2%) 4 (13.8%) 2 (50%) 10 (27.0%) 12 (27.9%) 1.00
 Deep Vein Thrombosis 0 0 0 0 0
 Pulmonary Embolism 0 0 0 0 0
 Smoking 17 (19.1%) 0 5 (15.2%) 5 (17.2%) 0 6 (16.2 8 (18.6%) 1.00
 Chronic Renal Disease 5 (5.6%) 0 1 (3.0%) 1 (3.4%) 0 5 (6.3%) 2 (4.7%) 0.658
 Creatinine Clearance – ml/min (mean ± SD) 81.8 ± 26.6 75.5 ± 24.5 87.6 ± 19.5 88.7 ± 20.2 80.0 ± 12.6 82.1 ± 26.1 81.8 ± 26.1 0.960
 Chronic Liver Disease 0 1 (10%) 0 0 0
 Chronic Lung Disease 6 (6.7%) 0 1 (3.0%) 0 0 1 (2.7%) 5 (11.6%) 0.209
 Active Endocarditis 14 (15.7%) 1 (10%) 0 0 0 10 (27.0%) 3 (7.0%) 0.030
 Previous Cardiac Surgery 7 (7.9%) 3 (30%) 0 0 0 3 (8.1%) 3 (7.0%) 1.00
 Poor Mobility 10 (11.2%) 4 (40%) 1 (3.0%) 1 (3.4%) 0 6 (16.2%) 4 (9.3%) 0.501