Table 2 Peri-operative and followup parameters of patients who underwent valve surgery via the use of CORKNOT®
Characteristics | Subclass distribution | Comparison group | ||||||
|---|---|---|---|---|---|---|---|---|
Variables | Valve Replacement (n = 89) | Combined Repair and replacement (n = 10) | Valve Repair (n = 33) | Single Mitral Valve Repair (n = 29) | Double Valve Repair (n = 4) | Single Mitral Valve Replacement (n = 37) | Single Aortic Valve Replacement (n = 43) | p-value |
Minimally Invasive Surgery | 31 (34.8%) | 2 (20%) | 25 (75.8%) | 22 (75.9%) | 3 (75%) | 17 (45.9%) | 13 (30.2%) | 0.170 |
Double Valve | 5 (5.6%) | 6 (60%) | 4 (12.1%) | – | – | – | – | – |
Triple Valve | 1 (1.1%) | 4 (40%) | – | – | – | – | – | – |
Operative Time – minutes (mean ± SD) | 317.4 ± 94.0 | 369.9 ± 132.6 | 311.7 ± 91.8 | 311.2 ± 94.2 | 315.5 ± 83.3 | 304.4 ± 74.7 | 311.0 ± 94.9 | 0.736 |
CPB Time – minutes (mean ± SD) | 168.3 ± 73.4 | 219.5 ± 95.7 | 164.8 ± 73.6 | 165 ± 78.1 | 163.3 ± 32.7 | 157.1 ± 68.0 | 167.2 ± 73.8 | 0.529 |
ACC Time – minutes (mean ± SD) | 108.9 ± 55.5 | 120.4 ± 40.8 | 93.4 ± 52.6 | 94.4 ± 55.6 | 86.3 ± 27.2 | 96.3 ± 45.1 | 111.6 ± 58.0 | 0.204 |
Hospital stay – days (mean ± SD) | 13.4 ± 11.7 | 21.8 ± 21.7 | 11.2 ± 5.4 | 11.3 ± 5.7 | 10.0 ± 2.2 | 14.1 ± 7.2 | 10.5 ± 11.6 | 0.018 |
ICU stay – days (mean ± SD) | 4.3 ± 5.0 | 7.5 ± 6.1 | 3.8 ± 2.2 | 3.8 ± 2.0 | 3.0 ± 3.4 | 3.8 ± 1.9 | 3.4 ± 1.8 | 0.263 |
Chest Tube duration – days (mean ± SD) | 4.9 ± 2.8 | – | 4.7 ± 1.4 | 4.6 ± 1.4 | – | 5.0 ± 2.3 | 4.1 ± 1.4 | 0.050 |
Immediate Post-operative Mild PVL or lessa | 3 (3.4%) | 0 | 0 | 0 | 0 | 0 | 3 (7.0%) | 0.245 |
Immediate Post-operative Significant PVL | 2 (2.2%) | 0 | 0 | 0 | 0 | 1 (2.7%) | 1 (2.3%) | 0.201 |
Stroke | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – |
Renal Failure | 9 (11.1%) | 2 (20%) | 1 (3.0%) | 1 (3.4%) | 0 | 4 (10.8%) | 4 (9.4%) | 0.352 |
Atrial Fibrillation | 29 (32.6%) | 2 (20%) | 13 (39.4%) | 11 (37.9%) | 2 (50%) | 16 (43.2%) | 9 (20.9%) | 0.052 |
PPM Insertionb | 6 (6.7%) | 2 (20%) | 4 (12.1%) | 3 (10.3%) | 1 (25%) | 2 (5.4%) | 3 (7.0%) | 1.00 |
Bleeding/Transfusion | 9 (10.1%) | 2 (20%) | 1 (3.0%) | 0 | 1 (25%) | 4 (10.8%) | 2 (4.7%) | 0.407 |
Thromboembolism | 0 | 1 (10%) | 0 | 0 | 0 | 0 | 0 | 0 |
Re-intervention | 9 (10.1%) | 0 | 2 (6.1%) | 1 (3.4%) | 1 (25%) | 2 (5.4%) | 3 (7.0%) | 1.00 |
Cardiac Mortality | 4 (4.5%) | 0 | 0 | 0 | 0 | 1 (2.7%) | 2 (4.7%) | 1.00 |
All-cause Mortality | 4 (4.5%) | 0 | 0 | 0 | 0 | 1 (2.7%) | 2 (4.7%) | 0.505 |
Follow-up TTE | ||||||||
Mild PVL or less | 0 | 0 | 0 | 0 | 0 | 1 (2.3%) | - | |
Ejection fraction (%) (mean ± SD) | 52.5 ± 11.4 | 53.- ± 10.1 | 52.8 ± 7.8 | 53.5 ± 7.8 | 47.5 ± 5.0 | 51.4 ± 10.0 | 53.7 ± 11.6 | 0.358 |
Thrombosis | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – |
Transvalvular regurgitation | 4 (4.5%) | 0 | 2 (6.1%) | 1 (3.4%) | 1 (25%) | 2 (5.4%) | 0 | 0.201 |