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Table 2 Peri-operative and followup parameters of patients who underwent valve surgery via the use of CORKNOT®

From: Incidence of valvular regurgitation and leaflet perforation by using automated titanium fasteners (CORKNOT®) in heart valve repair or replacement: less usual than reported

Characteristics Subclass distribution Comparison group
Variables Valve Replacement
(n = 89)
Combined
Repair and replacement
(n = 10)
Valve
Repair
(n = 33)
Single Mitral Valve Repair
(n = 29)
Double Valve Repair
(n = 4)
Single Mitral Valve Replacement
(n = 37)
Single Aortic Valve Replacement
(n = 43)
p-value
Minimally Invasive Surgery 31 (34.8%) 2 (20%) 25 (75.8%) 22 (75.9%) 3 (75%) 17 (45.9%) 13 (30.2%) 0.170
Double Valve 5 (5.6%) 6 (60%) 4 (12.1%)
Triple Valve 1 (1.1%) 4 (40%)
Operative Time – minutes (mean ± SD) 317.4 ± 94.0 369.9 ± 132.6 311.7 ± 91.8 311.2 ± 94.2 315.5 ± 83.3 304.4 ± 74.7 311.0 ± 94.9 0.736
CPB Time – minutes (mean ± SD) 168.3 ± 73.4 219.5 ± 95.7 164.8 ± 73.6 165 ± 78.1 163.3 ± 32.7 157.1 ± 68.0 167.2 ± 73.8 0.529
ACC Time – minutes (mean ± SD) 108.9 ± 55.5 120.4 ± 40.8 93.4 ± 52.6 94.4 ± 55.6 86.3 ± 27.2 96.3 ± 45.1 111.6 ± 58.0 0.204
Hospital stay – days (mean ± SD) 13.4 ± 11.7 21.8 ± 21.7 11.2 ± 5.4 11.3 ± 5.7 10.0 ± 2.2 14.1 ± 7.2 10.5 ± 11.6 0.018
ICU stay – days (mean ± SD) 4.3 ± 5.0 7.5 ± 6.1 3.8 ± 2.2 3.8 ± 2.0 3.0 ± 3.4 3.8 ± 1.9 3.4 ± 1.8 0.263
Chest Tube duration – days (mean ± SD) 4.9 ± 2.8 4.7 ± 1.4 4.6 ± 1.4 5.0 ± 2.3 4.1 ± 1.4 0.050
Immediate Post-operative Mild PVL or lessa 3 (3.4%) 0 0 0 0 0 3 (7.0%) 0.245
Immediate Post-operative Significant PVL 2 (2.2%) 0 0 0 0 1 (2.7%) 1 (2.3%) 0.201
Stroke 0 0 0 0 0 0 0
Renal Failure 9 (11.1%) 2 (20%) 1 (3.0%) 1 (3.4%) 0 4 (10.8%) 4 (9.4%) 0.352
Atrial Fibrillation 29 (32.6%) 2 (20%) 13 (39.4%) 11 (37.9%) 2 (50%) 16 (43.2%) 9 (20.9%) 0.052
PPM Insertionb 6 (6.7%) 2 (20%) 4 (12.1%) 3 (10.3%) 1 (25%) 2 (5.4%) 3 (7.0%) 1.00
Bleeding/Transfusion 9 (10.1%) 2 (20%) 1 (3.0%) 0 1 (25%) 4 (10.8%) 2 (4.7%) 0.407
Thromboembolism 0 1 (10%) 0 0 0 0 0 0
Re-intervention 9 (10.1%) 0 2 (6.1%) 1 (3.4%) 1 (25%) 2 (5.4%) 3 (7.0%) 1.00
Cardiac Mortality 4 (4.5%) 0 0 0 0 1 (2.7%) 2 (4.7%) 1.00
All-cause Mortality 4 (4.5%) 0 0 0 0 1 (2.7%) 2 (4.7%) 0.505
Follow-up TTE
 Mild PVL or less   0 0 0 0 0 1 (2.3%) -
Ejection fraction (%) (mean ± SD) 52.5 ± 11.4 53.- ± 10.1 52.8 ± 7.8 53.5 ± 7.8 47.5 ± 5.0 51.4 ± 10.0 53.7 ± 11.6 0.358
Thrombosis 0 0 0 0 0 0 0
Transvalvular regurgitation 4 (4.5%) 0 2 (6.1%) 1 (3.4%) 1 (25%) 2 (5.4%) 0 0.201
  1. aPVL paravalvular leak, bPPM Permanent pacemaker