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Table 3 Univariate and multivariate analysis of factors affecting AL after esophagectomy

From: Predictive value of postoperative C-reactive protein-to-albumin ratio in anastomotic leakage after esophagectomy

Variable Number (%) Univariate analysis Multivariate analysis
OR(95% CI) p value OR(95% CI) p value
Age (years)     0.995(0.925–1.069) 0.882
BMI (kg/m2)     0.918(0.735–1.147) 0.453
ASA score    0.014   0.169
 1 187(68.5) 1   1  
 2 72(26.4) 0.150(0.035–0.643)   0.143(0.017–1.182)  
 3 14(5.1) 0.872(0.186–4.097)   0.421(0.033–5.439)  
Operation type    0.006   0.246
 Open operation 137(50.2) 1   1  
 VATS 97(35.5) 3.694(1.601–8.522)   2.656(0.540–13.073)  
 RATS 39(14.3) 2.092(0.658–6.650)   0.693(0.103–4.686)  
Duration of operation (hours)    0.000   0.020
 <3.7 127(46.5) 1   1  
 ≥ 3.7 146(53.5) 17.544(4.111–74.861)   9.363(1.416–61.909)  
Postoperative WBC (109/L)    0.870   0.145
 <9.5 85(31.1) 1   1  
 ≥ 9.5 188(68.9) 0.938(0.435–2.023)   0.318(0.068–20.532)  
Postoperative RBC (1012/L)    0.114   0.155
 <4.0 134(49.1) 1   1  
 ≥ 4.0 139(50.9) 0.555(0.266–1.160)   3.562(0.618–20.532)  
Postoperative Hb (g/L)    0.001   0.121
 <120 130(47.6) 1   1  
 ≥ 120 143(52.4) 0.282(0.126–0.630)   0.246(0.042–1.446)  
Postoperative glucose (mmol/L)     0.945(0.772–1.156) 0.582
Postoperative CRP/ALB ratio    0.000   < 0.001
 <3.00 220(80.6) 1   1  
 ≥ 3.00 53(19.4) 70.435(22.790–217.687)   102.909(22.522–470.224)  
Postoperative NLR    0.088   0.788
 <18.38 165(60.4) 1   1  
 ≥ 18.38 108(39.6) 1.863(0.904–3.836)   1.318(0.176–9.874)  
Postoperative PLR    0.015   0.254
 <255.00 117(42.9) 1   1  
 ≥ 255.00 156(57.1) 2.725(1.186–6.264)   2.818(0.476–16.689)  
Postoperative LMR    0.070   0.851
 <1.04 129(47.3) 1   1  
 ≥ 1.04 144(52.7) 0.510(0.244–1.067)   0.843(0.142–5.024)  
Postoperative PNI    0.008   0.856
 <58.90 90(33.0) 1   1  
 ≥ 58.90 183(67.0) 0.383(0.185–0.794)   1.219(0.125–11.888)  
  1. Data are presented as n (%)
  2. OR odds ratio, CI confidence interval, BMI body mass index, ASA score American Society of Anesthesiologists (ASA) score, VATS video-assisted thoracic surgery, RATS robot-assisted thoracic surgery, WBC white blood cell, RBC red blood cell, Hb hemoglobin, CRP/ALB ratio C-reactive protein to albumin ratio, NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, LMR lymphocyte to monocyte ratio, PNI prognostic nutritional index