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Table 1 Preoperative baseline data of study group and control group

From: Coronary artery bypass graft surgery in patients on ticagrelor therapy is not associated with adverse perioperative outcomes

 

Group A

ASA alone

%(n = 106)

Group B

Ticagrelor +ASA

%(n = 55)

p-Value

Age (years)

64 ± 8

61 ± 10

0.034

Sex, Male (n,%)

87 (92)

96 (53)

0.092

Risk profile

 Diabetes Mellitus

42 (45)

47 (26)

0.622

 Hypertension

71 (75)

76 (42)

0.461

 Hyperlipidemia

75 (80)

76 (42)

0.850

 Smoking, current

38 (40)

54 (30)

0.002

 Smoking, past

12 (13)

5 (3)

0.267

 Obesity

16 (17)

25 (15)

0.207

Previous CAD

36 (38)

40 (22)

0.733

 Coronary stents in situ

26 (28)

51 (25)

0.003

 Paroxysmal atrial fibrillation

7 (7)

2 (1)

0.054

 Renal Failure

3 (3)

5 (3)

0.414

 Congestive heart failure

18 (19)

13 (7)

0.500

 Peripheral vascular disease

7 (7)

2 (1)

0.265

 Cerebrovascular accident

6 (6)

9 (5)

0.514

 COPD

6 (6)

5 (2)

0.716

Medications

 Aspirin

92 (97)

98(54)

0.137

 Anticoagulant therapy (VKA/DOACs)

8 (9)

2 (1)

0.254

 ACEi/ARB

48 (51)

61 (38)

0.002

 β Blockers

72 (76)

85 (47)

0.085

 Calcium Channel Blockers

26 (28)

27 (15)

0.854

  1. CAD Coronary artery disease, ASA acetylsalicylic acid, COPD chronic obstructive pulmonary disease, ACE angiotensin-converting enzyme, VKA Vitamin K antagonists, DOACs Direct oral anticoagulants