The effect of N-acetyl cysteine injection on renal function after coronary artery bypass graft surgery: a randomized double blind clinical trial

Table 3 Effect of administration of N-acetyl cysteine on hemodynamic variables

Parameter	N-acetyl cysteine group(n = 30)	Control group(n = 30)	P-Value
HR (beat/mi)
Baseline	78.20 ± 9.163	80.93 ± 11.608	0.685
4 h After surgery	76.07 ± 11.712	78.53 ± 10.391	0.872
48 h after surgery	75.67 ± 13.583	76.50 ± 8.842	0.896
P-Value	0.456	0.576
MAP (mmHg)
Baseline	119.77 ± 19.163	133.77 ± 24.241	0.324
4 h After surgery	92.87 ± 12.190	98.10 ± 22.550	0.002 *
48 h after surgery	82.20 ± 14.346	85.80 ± 13.499	< 0.001 *
P-Value	< 0.05*	< 0.05*
U.OP (cc)
Baseline	250.00 ± 125.945	220.33 ± 125.382	0.364
4 h After surgery	324.00 ± 124.224	306.33 ± 167.548	0.644
48 h after surgery	1161.67 ± 372.708	1032.00 ± 448.179	0.228
P-Value	< 0.001*	< 0.001*

NAC N-acetyl cysteine, HR Heart rate, MAP Mean arterial pressure, U.OP: Urine out put
Data are expressed as mean ± SD. The statistical test used was the t-test and repeated measurement. P < 0.05; t-test analysis and repeated measurement demonstrated difference between the groups with *

ISSN: 1749-8090