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Table 2 results of meta-analyses of prediction value

From: The D-dimer level predicts the prognosis in patients with lung cancer: a systematic review and meta-analysis

Survival outcome No HR [95% CI] Log-rank p Heterogeneity (p, I2(%)) Publication bias
OS 27 1.742(1.542,1.969)  < 0.001  < 0.001,72.1% 0.871
location      
Asia 20 1.979(1.646,2.379)  < 0.001  < 0.001,75.3%  
Europe 3 1.504(1.335,1.695)  < 0.001 0.623,0.0%  
Oceania 2 1.572(0.899,2.746) 0.112 0.111,60.6  
Histology type (adenocarcinoma/total > 25%)      
Yes 8 1.639(1.298,2.069)  < 0.001  < 0.001,71.8%  
No 15 1.976(1.651,2.364)  < 0.001  < 0.001,75.3%  
Tumor stage (III + IV/total > 80%)      
Yes 9 1.681(1.377,2.053)  < 0.001  < 0.001,78.0%  
No 8 1.352(1.265,1.445)  < 0.001 0.065,47.4%  
Detection method      
ELISA 7 2.144(1.466,3.134)  < 0.001  < 0.001,74.4%  
latex assay 4 1.513(1.266,1.810)  < 0.001 0.026,67.6%  
immunoturbidimetry assay 10 1.363(1.264,1.470)  < 0.001 0.065,44.1%  
Surgery      
Non-surgical 8 2.380(1.78,3.18)  < 0.001 0.019,58.2%  
surgical 4 1.910(1.17,3.14)  < 0.001 0.008,74.5%  
mixed 5 1.688(1.333,2.139)  < 0.001 0.020,65.6%  
PFS 7 1.385(1.169,1.641)  < 0.001 0.003,69.1%  
location      
Asia 6 1.461(1.148,1.861) 0.002 0.007,68.5%  
Europe 1 1.340(1.167,1.539)  < 0.001   
Histology type (adenocarcinoma/total > 25%)      
Yes 1 1.340(1.167,1.539)  < 0.001   
No 6 1.461(1.148,1.861) 0.002 0.007,68.5%  
Tumor stage (III + IV/total > 80%)      
Yes 3 1.431(1.022,2.004) 0.037 0.005,81.1%  
No 1 2.400(1.413,4.078) 0.001   
Detection method      
latex assay 1 1.340(1.167,1.539)  < 0.001   
immunoturbidimetry assay 6 1.461(1.148,1.861) 0.002 0.007,68.5%%  
Surgery      
Non-surgical 5 1.310(1.076,1.596) 0.007 0.074,53.0%  
mixed 1 2.400 (1.413,4.078) 0.001