Balanced forced-diuresis compared to control as a reno-protective approach in cardiac surgery: secondary outcome of a randomized controlled trial, assessment of neutrophil gelatinase-associated lipocalin levels

Table 1 Pre, peri and post-operative characteristics of patients in the two groups

	RG group (n = 110)	Control group (n = 110)	p value
Pre-op creatinine^a, micromol/L	99.0 (28.2)	98.3 (34.7)	0.29
Pre-op eGFR^a, ml/min/1.73m²	66.5 (17.2)	68.2 (20.3)	0.47
Pre-op Haemoglobin^a, g/L	135 (16)	134 (18)	0.72
Logistic EuroScore^b	3.8 (0.9, 67.4)	3.2 (0.9, 32.5)	0.3
Age^a, years	67.8 (9.3)	67.0 (9.2)	0.33
Pre-op NGAL level^b, (ng/ml)	83 (19, 202)	86(15,459)	0.64
Male, (n, %)	87, 79%	84, 76%	0.63
Non-diabetics, (n, %)	30, 27%	30, 27%	0.66
Impaired LVEF, (n, %)	51, 46%	38, 34%	0.14
Urgent surgery, (n, %)	34, 31%	24, 22%	0.13
Combined operations, (n, %)	40,37%	31, 28%	0.38
ecDO₂i^a, ml/min/m²	300 (52)	300 (52)	0.73
ecVCO₂^a, ml/min/m²	70 (24)	71 (21)	0.92
XCT time^a, mins	84 (40)	79 (42)	0.25
Serum lactate during surgery^b, mmol/L	1.97 (0.78,5.00)	1.80 (0.87,4.98)	< 0.01
Serum lactate on CICU^b, mmol/L	1.8 (0.60, 6.80)	1.7 (0.6, 8.70)	0.14
CICU stay^b, hours	27 (16, 410)	28 (8, 486)	0.92
Atrial Fibrillation, (n/total, %)	12/108, (11%)	10/108, (9%)	0.62
Blood transfusion, (n/total, %)	29/108, (27%)	21/109, (19%)	0.16
Infection, (n/total,%)	10/108, (9%)	8/108, (7%)	0.59
In-hospital survival, (n/total, %)	109/110 (99%)	108/110 (98%)	0.56

Table showing the patients’ characteristics for the two groups along with the intra-operative data and post-operative complications rates
e-GFR estimated glomerular filtration rate, NGAL neutrophil gelatinase-associated lipocalin, LVEF left ventricular ejection fraction, ecDO2i oxygen delivery, ecVCO2i CO2 production during the CPB, XCT cross clamp time, CICU cardiac intensive care unit
^aDenotes mean (SD)
^bDenotes median (minimum, maximum)

ISSN: 1749-8090