Table. 4 Outcomes and hepatorenal function in matched cohort
Variable | Bilirubin adsorption (n = 14) | Plasma exchange (n = 14) | P value | |
|---|---|---|---|---|
Death (n, %) | 10, 71.4% | 14, 100.0% | 0.049 | |
CRRT (n, %) | 12, 85.7% | 12, 85.7% | — | |
IABP (n, %) | 3, 21.4% | 8, 57.15% | 0.060 | |
ECMO (n, %) | 3, 21.4% | 3, 21.4% | — | |
Re-intubation (n, %) | 9, 64.2% | 10, 71.4% | 0.500 | |
Septic shock (n, %) | 5, 35.7% | 4, 28.6% | 0.500 | |
Ventricular arrhythmias (n, %) | 9, 64.2% | 6, 42.9% | 0.225 | |
Hepatic encephalopathy (n, %) | 5, 35.7% | 13, 92.9% | 0.002 | |
Peak VIS after adsorption/exchange | 47.3 ± 5.9 | 62.9 ± 19.8 | 0.013 | |
Peak lac adsorption/exchange (mmol/L) | 8.4 ± 2.2 | 10.1 ± 2.1 | 0.045 | |
After adsorption/exchange | ||||
ALT | 28.9 (19.4–64.0) | 42.1 (32.9–94.0) | 0.021 | |
AST | 58.0 (46.6–74.5) | 76.3 (60.3–101.7) | 0.012 | |
GGT | 69.0 (20.0–118.5) | 79.0 (30.0–125.3) | 0.667 | |
TBil | 162.9 ± 76.3 | 235.2 ± 82.9 | 0.024 | |
DBil | 90.4 ± 35.2 | 139.1 ± 53.5 | 0.009 | |
LDH | 394.5 ± 127.8 | 435.1 ± 161.7 | 0.467 | |
Serum Creatinine | 80.1 ± 11.9 | 107.8 ± 22.8 | 0.001 | |
BUN | 10.3 ± 2.8 | 14.5 ± 4.3 | 0.010 | |
C-creative protein | 83.5 ± 15.8 | 151.6 ± 49.2 | 0.018 | |