Low postoperative blood platelet count may be a risk factor for 3-year mortality in patients with acute type A aortic dissection

Table 3 Factors in association with postoperative death in follow up

	Univariate analyses^a		Multivariate analysis^b
	OR (95% CI)	P value	OR (95% CI)	P value
Age, year	1.040 (1.009, 1.072)	0.012	–	–
Gender, male	2.013(1.034, 3.921)	0.040	3.213 (1.426, 7.240)	0.005
CPB duration, min	1.009 (1.003, 1.014)	0.002	1.008 (1.002, 1.015)	0.012
Red blood cells infusion, U	1.200 (1.066, 1.351)	0.003	–	–
Fresh frozen plasma infusion, ml	1.001 (1.000, 1.001)	0.007	–	–
Postoperative platelets count, 10*10⁹/L	0.897 (0.837, 0.961)	0.002	0.918(0.853, 0.988)	0.023
Reoperation for hemostasis	4.443 (1.504, 13.128)	0.007	–	–
Reoperation for other reasons*	5.511 (2.238, 13.572)	< 0.001	–	–
Readmission to ICU	5.476 (1.967, 15.245)	0.001	3.751 (1.055, 13.332)	0.041
Postoperative cardiac insufficiency	19.693 (4.532, 85.572)	0.001	13.614 (2.124, 87.248)	0.006
Postoperative complications of the CNS	5.534 (2.898, 10.567)	< 0.001	2.986 (1.411, 6.319)	0.004
Postoperative complications of the respiratory system	6.514 (3.370, 12.592)	< 0.001	3.976 (1.860, 8.498)	< 0.001
Postoperative infection	2.206 (1.073, 3.826)	0.030	–	–

CPB, Cardiopulmonary bypass, ICU, Intensive care unit, CNS, Central nervous system
^*Other postoperative operations other than postoperative hemostasis
^aPostoperative death was modeled as a function of a single factor in the univariate logistic regression analyses
^bPostoperative death was modeled as a function of several factors with a P value < 0.10 in the univariate analyses. Multivariate Logistic regression analysis was performed using a Backward stepwise procedure. Hosmer–Lemeshow test of goodness of fit of the model: χ² = 1.98, df = 6, P = 0.922

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