Skip to main content

Table 4 Preoperative and operative risk factors for Western versus Developing worlds

From: PROSE: Prospective Randomized Trial of the On-X Mechanical Prosthesis and the St Jude Medical Mechanical Prosthesis Evaluation

Factor

Whole study

Western

Developing

p Value

Smoker (N—%)

303–35.4

231–52.9

72–17.2

 < 0.0001

Coronary disease in family (N—%)

145–17.0

127–29.1

18–4.3

 < 0.0001

Diabetes (N—%)

98–11.5

66–15.1

32–7.7

0.0004

High cholesterol (N—%)

221–25.8

193–44.2

28–6.7

 < 0.0001

Preoperative creatinine (mean—SD)

89.8–65.1

98.1–91.0

83.1–28.4

0.001

Renal failure (N—%)

35–4.1

19–4.3

16–3.8

0.711

Hypertension (N—%)

329–38.5

243–55.6

86–20.6

 < 0.0001

History of CVA (N—%)

45–5.3

24–5.5

21–5.0

0.743

Previous endocarditis (N—%)

37–4.3

19–4.3

18–4.3

0.989

Existing COPD (N—%)

81–9.5

61–14.0

20–4.8

 < 0.0001

Immunosuppressed (N—%)

12–1.4

11–2.5

1–0.2

0.003

Peripheral vascular disease (N—%)

23–2.7

18–4.1

5–1.2

0.009

Carotid vascular disease (N—%)

45–5.3

26–5.9

19–4.6

0.395

Previous cardiac surgery (N—%)

124–14.5

54–12.4

71–17.0

0.057

Previous MI (N—%)

41–4.8

36–8.2

5–1.2

 < 0.0001

Congestive heart failure (N—%)

217–25.4

95–21.7

122–29.3

0.011

Angina (N—%)

116–13.6

90–20.6

26–6.2

 < 0.0001

Cardiogenic shock (n—%)

4–0.5

1–0.2

3–0.7

0.272

Resuscitation (N—%)

5–0.6

2–0.5

3–0.7

0.705

Ejection fraction % (mean—SD)

55.5–11.5

56.3–12.9

54.9–10.2

0.080

Preoperative Status (N—%)

Elective

657–84.0

321–88.2

336–80.4

0.023

Urgent

119–15.2

40–11.0

79–18.9

 

Emergent

6–0.8

3–0.8

3–0.7

 

Aortic valve percentage

502–58.7

381–87.2

121–29.0

 < 0.0001

Concomitant procedures (N—%)

286–33.4

133–30.4

153–36.7

0.051

Intraoperative AE’s (N—%)

76–8.9

56–12.8

20–4.8

 < 0.0001

  1. p-value considered significant when < 0.05 and highlighted in those cases