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Table 5 Oxford grades [26]

From: Systematic literature review evaluating evidence and mechanisms of action for platelet-rich plasma as an antibacterial agent

A

Consistent level 1 studies

B

Consistent level 2 or 3 studies or extrapolations from level 1 studies

C

Level 4 studies or extrapolations from level 2 or 3 studies

D

Level 5 evidence or troublingly inconsistent or inconclusive studies of any level

  1. Users can add a minus-sign “ − ” to denote the level that fails to provide a conclusive answer because: either a single result with a wide confidence interval or a systematic review with troublesome heterogeneity such evidence is inconclusive, and therefore can only generate graded recommendations
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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