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Table 7 Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) evaluation of bias for preclinical studies

From: Systematic literature review evaluating evidence and mechanisms of action for platelet-rich plasma as an antibacterial agent

Author year

Selection bias

Performance bias

Detection bias

Attrition bias: complete outcome data?

Reporting bias: non-selective outcome reporting?

No other sources of bias?

Randomization?

Random sequence generation?

Baseline characteristics equal?

Allocation concealment?

Random housing?

Blinding?

Random selection outcome assessment?

Blinding?

Yassin, 2019 [48]

No

No

No

No

No

No

No

No

Yes

Yes

Yes

Farghali, 2018 [50]

No

No

Yes

No

No

No

No

No

Yes

Yes

Yes

Shibata, 2018 [37]

Yes

No

Yes

No

No

No

No

No

Yes

Yes

Yes

Nimal, 2016 [47]

No

No

No

No

No

No

No

No

Yes

Yes

Yes

Cetinkaya, 2018 [45]

Yes

No

Yes

No

No

No

No

No

Yes

Yes

Yes

  1. “Yes” indicates reduced bias and “No” indicates increased bias