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Table 8 Power and sample size calculations (2-tailed)

From: Systematic literature review evaluating evidence and mechanisms of action for platelet-rich plasma as an antibacterial agent

 

Required sample size a priori

Achieved power post hoc

Input

 Proportion p2

0.01

0.016

0.026

 Proportion p1

0.03

0.006

0.1

 α err prob

0.05

0.05

0.05

 Power (1 − β err prob)

0.8

0.8

–

 Allocation ratio N2/N1

1

1

–

 Sample size group 1

–

–

1000

 Sample size group 2

–

–

1000

Output

 Critical z

1.9599640

1.9599640

 − 1.9599640

 Power (1 − β err prob)

–

–

0.9999995

 Sample size group 1

769

1707

–

 Sample size group 2

769

1707

–

 Total sample size

1538

3414

–

 Actual power

0.8005067

0.8000975

–

  1. z tests—proportions: difference between 2 independent proportions [4, 56]