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Table 4 The registered trials of vein-first versus artery-first ligation in lung cancer surgery

From: Vein-first versus artery-first ligation procedure for lung cancer surgery: An updated review

Identifier

Year

Neoadjuvant chemotherapy or radiotherapy

Staging

Surgical procedure

Study design

Estimated enrollment

Major outcomes

Status

Country

NCT00341380

2006

Not mentioned

Stage I ~ II

Resection of non-small cell lung tumor

Prospective cohort study

41

Postoperative metastases/recurrence

Completed

America

NCT03645252 (CTC-01)

2018

None

cT1 ~ 3N0M0

Lobectomy/bi-lobectomy

Randomized pilot study

30

The change of CTC in pulmonary vein; DFS; OS

Not yet recruiting

Canada

NCT03436329

2018

None

Stage I–IV eligible for surgery

Lobectomy

Multi-centre randomized controlled trial

60

CTC level before cutting the skin and after closing the chest; 3-year PFS; complications

Not yet recruiting

China

ChiCTR1800016879

2018

None

cT1a-2aN0M0

Lobectomy

Non-randomized cohort study

60

The change of CTC level

Recruiting

China

  1. CTC, circulating tumor cell; PFS, progression-free survival; DFS, disease-free survival; OS, overall survival