Table 3 Clinical results and macroscopic findings following maximal aortic pressures on CPB
From: The susceptibility of the aortic root: porcine aortic rupture testing under cardiopulmonary bypass
Swine number | Surgical approach | Cannulation | CPB flows (L/min) | Maximal pressure | Macroscopic findings |
|---|---|---|---|---|---|
1 | Right thoracotomy | Arterial—ascending aorta Venous—Right atrium | 2L | 280 mmHg | Valvular failure with no evidence of cusp tearing Cusp hemorrhage present Superior Vena Cava (SVC) tearing resulting in exsanguination of subject |
2 | Median sternotomy | Arterial—ascending aorta Venous—right atrium | 2.2L | 286 mmHg | Non-coronary cusp tearing and valvular rupture Cusp hemorrhage Subject euthanized |
3 | Median sternotomy | Arterial—ascending aorta Venous—right atrium | 4.3L | 500 mmHg | Non-coronary cusp tearing and valvular rupture Cusp hemorrhage Subject euthanized |
4 | Median sternotomy | Arterial—ascending aorta Venous—right atrium | 5.4L | 505 mmHg | Non-coronary cusp tearing and valvular rupture Subject euthanized |
5 | Median sternotomy | Arterial—ascending aorta Venous—right atrium | 3.96L | 497 mmHg | Non-coronary cusp tearing and valvular rupture Cusp hemorrhage Subject euthanized |
Median | 3.96L | 497 mmHg |