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Table 3 Clinical results and macroscopic findings following maximal aortic pressures on CPB

From: The susceptibility of the aortic root: porcine aortic rupture testing under cardiopulmonary bypass

Swine number Surgical approach Cannulation CPB flows (L/min) Maximal pressure Macroscopic findings
1 Right thoracotomy Arterial—ascending aorta
Venous—Right atrium
2L 280 mmHg Valvular failure with no evidence of cusp tearing
Cusp hemorrhage present
Superior Vena Cava (SVC) tearing resulting in exsanguination of subject
2 Median sternotomy Arterial—ascending aorta
Venous—right atrium
2.2L 286 mmHg Non-coronary cusp tearing and valvular rupture
Cusp hemorrhage
Subject euthanized
3 Median sternotomy Arterial—ascending aorta
Venous—right atrium
4.3L 500 mmHg Non-coronary cusp tearing and valvular rupture
Cusp hemorrhage
Subject euthanized
4 Median sternotomy Arterial—ascending aorta
Venous—right atrium
5.4L 505 mmHg Non-coronary cusp tearing and valvular rupture
Subject euthanized
5 Median sternotomy Arterial—ascending aorta
Venous—right atrium
3.96L 497 mmHg Non-coronary cusp tearing and valvular rupture
Cusp hemorrhage
Subject euthanized
Median    3.96L 497 mmHg