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Table 1 Comparison of preoperative variables

From: Hepatic dysfunction in patients who received acute DeBakey type I aortic dissection repair surgery: incidence, risk factors, and long-term outcomes

Variables

Total (n = 634)

MELD < 14 (n = 233)

MELD ≥ 14 (n = 401)

P Valuea

Demographic data

    

 Age (year)

53.0 ± 12.4

53.4 ± 12.1

52.8 ± 12.6

0.348

 Male (%)

480 (75.7)

161 (69.1)

319 (79.6)

0.003

 BMI (kg/m2)

26.4 ± 4.7

26.1 ± 4.3

26.5 ± 4.9

0.243

Medical history

    

 Hypertension (%)

492 (77.6)

178 (76.4)

314 (78.3)

0.578

 Diabetes mellitus (%)

15 (2.4)

7 (3.0)

8 (2.0)

0.420

 Previous cardiac surgery (%)

30 (4.7)

11 (4.7)

19 (4.7)

0.992

 Previous cardiovascular disease (%)

20 (3.2)

6 (2.6)

14 (3.5)

0.525

 Cerebrovascular disease (%)

24 (3.8)

10 (4.7)

14 (3.2)

0.347

MELD score

16.8 (11.9, 22.4)

11.2 (9.4, 12.5)

20.6 (17.1, 26.4)

< 0.001

Time from onset to surgery (h)

16.8 ± 5.2

17.4 ± 7.2

16.3 ± 6.4

0.644

Pericardial tamponade (%)

110 (17.4)

37 (15.9)

73 (18.2)

0.456

Involving the celiac trunk (%)

134 (21.1)

47 (20.2)

87 (21.7)

0.676

Involving the superior mesenteric artery (%)

120 (18.9)

43 (18.5)

78 (19.2)

0.703

Preoperative laboratory data

    

 WBC (109/L)

11.5 (8.8, 14.3)

11.0 (8.7, 13.4)

11.7 (8.8, 14.9)

0.038

 Hemoglobin (g/L)

124.2 ± 24.6

127.2 ± 20.7

122.4 ± 26.5

0.102

 PLT (109/L)

153.2 ± 94.5

166.9 ± 126.5

145.4 ± 68.7

< 0.001

 Fibrinogen (g/L)

2.2 (1.6, 3.0)

2.5 (1.8, 3.5)

2.0 (1.5, 3.0)

< 0.001

 Triglyceride (mmol/L)

1.1 (0.7, 1.5)

1.1 (0.7, 1.5)

1.1 (0.8, 1.5)

0.841

 CRP (mg/dl)

23.7 (4.9, 84.4)

22.0 (4.4, 80.0)

30.3 (5.8, 88.4)

0.148

 TNT (ng/ml)

0.02 (0.01, 0.11)

0.01 (0.01, 0.03)

0.03 (0.01, 0.16)

< 0.001

 D-dimer (ng/mL)

4.9 (2.7, 9.9)

4.2 (2.1, 7.5)

5.1 (3.0, 11.7)

0.005

 Albumin (g/L)

36.8 ± 5.0

37.9 ± 4.1

36.2 ± 5.3

0.001

 ALT (U/L)

25.1 (16.2, 44.5)

20.4 (15.1, 35.7)

29.0 (17.2, 52.3)

< 0.001

 AST (U/L)

31.2 (21.0, 53.6)

26.0 (19.0, 41.3)

33.3 (22.0, 72.0)

< 0.001

 Cr (μmol/L)

100.1 ± 65.7

68.2 ± 19.8

118.6 ± 75.2

< 0.001

 Bun (mmol/L)

8.1 ± 3.6

6.7 ± 2.4

9.0 ± 3.9

< 0.001

 Total bilirubin (μmol/L)

15.3 (11.2, 22.8)

13.7 (10.5, 20.0)

16.6 (11.8, 23.9)

0.001

 INR

1.08 (1.00, 1.20)

1.05 (0.97, 1.12)

1.13 (1.03, 1.25)

< 0.001

  1. Bold values indicate significance at p < 0.05
  2. Data presented as n (%), median (IQR), or means ± standard deviation
  3. BMI body mass index, WBC white blood cell, PLT platelet, CRP c-reactive protein, TNT troponin T, ALT alanine transaminase, AST aspartate transaminase, Cr creatinine, Bun blood urea nitrogen, INR international normalized ratio
  4. aP values indicate differences between HD patients and non-HD patients. P < 0.05 was considered statistically significant
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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