Table 6 The results of meta-analysis of postoperative outcomes (ViMAC vs ViR)
Outcomes | Studies | Effect measure | Model | Participants | Effect estimate | LCI | UCI | Q | P(Q) | Z | P(Z) |
|---|---|---|---|---|---|---|---|---|---|---|---|
All-cause Mortality within 30 days | 4 | Odds ratio | Fixed | 470 | 3.20 | 1.89 | 5.43 | 3.27 | 0.35 | 4.32 | < 0.01 |
 Cardiovascular | 2 | Odds ratio | Fixed | 244 | 1.96 | 0.78 | 4.96 | 0.38 | 0.54 | 1.43 | 0.15 |
 Noncardiovascular | 2 | Odds ratio | Fixed | 244 | 2.01 | 0.70 | 5.80 | 0.01 | 0.91 | 1.29 | 0.20 |
 Unknown-cause | 2 | odds ratio | Fixed | 226 | 4.94 | 2.33 | 10.46 | 0.07 | 0.79 | 4.17 | < 0.01 |
Bleeding | 4 | Odds ratio | Random | 489 | 0.62 | 0.17 | 2.17 | 9.72 | 0.02 | 0.75 | 0.45 |
 Minor | 1 | Odds ratio | Fixed | 40 | 2.36 | 0.11 | 52.88 | 0.00 | 1.00 | 0.54 | 0.59 |
 Major or extensive bleeding | 4 | Odds ratio | Fixed | 489 | 1.20 | 0.43 | 3.35 | 1.22 | 0.75 | 0.35 | 0.73 |
 Life-threatening or fatal | 3 | Odds ratio | Fixed | 462 | 0.76 | 0.36 | 1.60 | 0.44 | 0.80 | 0.73 | 0.46 |
Embolization | 4 | Odds ratio | Fixed | 489 | 1.92 | 0.71 | 5.19 | 2.46 | 0.48 | 1.29 | 0.20 |
Conversion to Cardiac surgery | 3 | Odds ratio | Fixed | 449 | 1.38 | 0.54 | 3.53 | 3.02 | 0.22 | 0.67 | 0.51 |
Left ventricular outflow tract obstruction | 4 | Odds ratio | Random | 489 | 3.02 | 0.82 | 11.05 | 10.14 | 0.02 | 1.67 | 0.10 |
Stroke | 3 | Odds ratio | Fixed | 462 | 5.16 | 1.14 | 23.38 | 1.88 | 0.39 | 2.13 | 0.03 |
Post-procedural echocardiographic findings | |||||||||||
 LVEF (%) | 2 | Mean difference | Fixed | 226 | 13.64 | 10.02 | 17.26 | 0.00 | 0.95 | 7.39 | < 0.01 |
 Mitral valve mean gradient (mmHg) | 2 | Mean difference | Fixed | 226 | − 1.54 | − 2.38 | − 0.71 | 1.14 | 0.28 | 3.62 | < 0.01 |
 Right ventricular systolic pressure (mmHg) | 1 | Mean difference | Fixed | 27 | − 1.00 | − 13.57 | 11.57 | 0.00 | 1.00 | 0.16 | 0.88 |
 MVA, mitral valve area (cm2) | 2 | Mean difference | Fixed | 226 | 0.65 | 0.36 | 0.93 | 1.01 | 0.31 | 4.45 | < 0.01 |
 Vascular complication | 3 | Odds ratio | Fixed | 462 | 1.31 | 0.54 | 3.16 | 1.05 | 0.59 | 0.60 | 0.55 |
 Acute kidney injury | 2 | Odds ratio | Fixed | 239 | 1.35 | 0.53 | 3.44 | 0.00 | 1.00 | 0.63 | 0.53 |
 Need for second valve implantation | 3 | Odds ratio | Random | 449 | 1.06 | 0.34 | 3.31 | 4.41 | 0.11 | 0.09 | 0.92 |
Postprocedural mitral regurgitation | |||||||||||
 Trace/none | 1 | Odds ratio | Fixed | 223 | 1.16 | 0.69 | 1.98 | 0.00 | 1.00 | 0.56 | 0.57 |
 1 (+) | 1 | Odds ratio | Fixed | 223 | 1.01 | 0.58 | 1.75 | 0.00 | 1.00 | 0.04 | 0.97 |
 2 (+) or greater | 1 | Odds ratio | Fixed | 223 | 0.82 | 0.13 | 4.98 | 0.00 | 1.00 | 0.22 | 0.83 |