Table 4 Uni- and multivariate analyses of prognostic factors of worse survival after single pulmonary metastasectomy (PM)
From: Survival prognostic and recurrence risk factors after single pulmonary metastasectomy
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Female sex | 1.27 (0.69–2.34) | 0.45 | ||
Age > 70 years | 0.83 (0.39–1.75) | 0.62 | ||
Non-colorectal tumour | 2.44 (1.12–5.29) | 0.02 | 2.40 (1.11–5.22) | 0.03 |
Previous extra-thoracic metastases | 0.81 (0.42–1.56) | 0.55 | ||
Chemotherapy before first PM | 1.00 (0.54–1.85) | 0.99 | ||
DFI1 < 12 months | 1.32 (0.66–2.65) | 0.43 | ||
Synchronous metastasis | 1.97 (0.82–4.70) | 0.13 | ||
VATS | 1.04 (0.44–2.48) | 0.93 | ||
Wedge resection | 0.93 (0.47–1.86) | 0.84 | ||
Margins of the pulmonary metastasis < 5 mm | 0.80 (0.43–1.49) | 0.48 | ||
Size of the pulmonary metastasis < 20 mm | 0.96 (0.43–2.18) | 0.93 | ||
Mediastinal lymph nodes involvement | 3.60 (1.08–12.03) | 0.04 | 3.42 (1.03–11.41) | 0.04 |