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Table 1 Baseline characteristics

From: Video-assisted thoracoscopic lobectomy versus open lobectomy in the treatment of large lung cancer: propensity-score matched analysis

Variables Unmatched cohort Propensity score-matched cohort
Thoracotomy (n = 223) VATS (n = 132) P value Thoracotomy (n = 102) VATS (n = 102) P value
Age 68 (61.0–73.0) 66 (59.8–71.0) 0.139 67 (61.0–72.0) 67 (60.0–72.0) 0.871
Sex       
Female 27 (12.1%) 36 (27.3%)  < 0.001 17 (16.7%) 18 (17.6%)  > 0.999
Male 196 (87.9%) 96 (72.7%) 85 (83.3%) 84 (82.4%)
Smoking       
Never 27 (12.1%) 43 (32.6%)  < 0.001 19 (18.6%) 25 (24.5%) 0.829
Former 102 (45.7%) 55 (41.7%) 44 (43.1%) 47 (46.1%)
Current 94 (42.1%) 34 (25.8%) 39 (38.2%) 30 (29.4%)
FEV1 (%)       
 ≥ 80% 51 (22.9%) 20 (15.2%) 0.079 81 (79.4%) 84 (82.4%) 0.701
 < 80% 172 (77.1%) 112 (84.9%)   21 (20.6%) 18 (17.6%)  
DLCO (%)       
 ≥ 80% 26 (11.7%) 8 (6.1%) 0.083 91 (89.2%) 94 (92.2%) 0.607
 < 80% 197 (88.3%) 124 (93.9%) 11 (10.8%) 8 (7.8%)
CCI       
0 146 (65.5%) 88 (66.7%) 0.627 66 (64.7%) 64 (62.7%) 0.809
1 49 (22.0%) 31 (23.5%) 26 (25.5%) 27 (26.5%)
2 18 (8.1%) 6 (4.5%) 5 (4.9%) 5 (4.9%)
 ≥ 3 10 (4.5%) 7 (5.3%) 5 (4.9%) 6 (5.9%)
Tumor size 61 (55.0–75.0) 57(54.0–65.0)  < 0.001 59 (54.3–68.5) 59 (54.0–67.0) 0.777
Location       
RUL 53 (23.8%) 29 (22.0%) 0.060 20 (19.6%) 22 (21.6%) 0.106
RML 2 (0.9%) 7 (5.3%) 2 (2%) 7 (6.9%)
RLL 54 (24.2%) 40 (30.3%) 25 (24.5%) 32 (31.4%)
LUL 56 (25.1%) 26 (19.7%) 26 (25.5%) 20 (19.6%)
LLL 58 (26.0%) 30 (22.7%) 29 (28.4%) 21 (20.6%)
Histology       
ADC 90 (40.4%) 88 (66.7%)  < 0.001 62 (60.8%) 63 (61.8%)  > 0.999
SCC 108 (48.4%) 30 (22.7%) 28 (27.5%) 26 (25.5%)
Others 25 (11.21%) 14 (10.61%) 12 (11.8%) 13 (12.7%)
  1. Data are presented as number (%), or median (interquartile range)
  2. FEV1 forced expiratory volume at 1 s, DLCO diffusing capacity for carbon monoxide, CCI Charlson comorbidity index, ADC adenocarcinoma, SCC squamous cell carcinoma, VATS video-assisted thoracic surgery